نتایج جستجو برای: intractable seizure
تعداد نتایج: 36457 فیلتر نتایج به سال:
High-gamma (HG; 80-150 Hz) activity in macroscopic clinical records is considered a marker for critical brain regions involved in seizure initiation; it is correlated with pathological multiunit firing during neocortical seizures in the seizure core, an area identified by correlated multiunit spiking and low frequency seizure activity. However, the effects of the spatiotemporal dynamics of seiz...
Aicardi syndrome (AS) is characterized by the triad of agenesis of the corpus callosum, infantile spasms, and chorio-retinal lacunae. AS patients often exhibit multiple seizures types, which are typically pharmacoresistant. We present the case of a 6 year-old girl with likely AS, developmental delays, and medically refractory epilepsy who was found to have diffuse MRI abnormalities characterist...
We review our experience with high-dose intravenous levetiracetam (IV-LEV) for acute seizure exacerbations in nine children with medically intractable epilepsy. All children had acute repetitive seizures-while on chronic antiepileptic drugs-that either led to hospitalization (eight) or occurred during hospitalization (one), and received doses of IV-LEV of 150 mg/kg/day or greater, with a mean d...
RATIONALE: Felbamate (FBM) use has declined since 1994 following reports of FBM induced aplastic anemia and liver failure. Limited published data is available on the clinical experience of FBM use since 1994. We previously presented a preliminary report on a limited sample of adult patients treated at Minnesota Epilepsy Group. The current study significantly expands our observations on Felbamat...
Ictal dancing is a very rare seizure semiology. Five cases have been previously reported in the literature [1–4]. Even though one case report investigated with stereo-encephalography (SEEG) showing intracranial ictal EEG change arising from right prefrontal region, particularly right dorsolateral prefrontal area in patients with ictal singing associated with dancing, underlying mechanisms and t...
Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive enzyme defect in the vitamin B6 metabolism characterized by intractable seizures which are usually resistant to all antiepileptic drugs but respond to pharmacological doses of pyridoxine. We present the clinical and molecular genetic findings of two patients with c.1597_1597delG mutations in ALDH7A1 gene. There are different clin...
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