Professor Wald and his team (Wald et al., 2004) have remodelled the already modelled SURUSS data (Wald et al., 2003a) to claim, firstly, that their results are now similar to those of the multicentre study co-ordinated by the Fetal Medicine Foundation (Snijders et al., 1998), and, secondly, that the gestation of choice for nuchal translucency (NT) measurement is 10 weeks. The latest modelling e...

AIM To evaluate the prevalence of increased nuchal translucency (NT) in multiple pregnancies and its relation to fetal karyotype and pregnancy outcome. METHODS We measured fetal nuchal translucency (NT) in 6,338 women pregnant from 10+3 to 13+6 weeks by ultrasound and evaluated the prevalence of NT=95th centile in 115 multiple pregnancies, including 100 pairs of twins (70 dichorionic and 30 m...

OBJECTIVE Assess the accuracy of the nuchal translucency (NT) measurement between 11 and 13 weeks and 6 days of gestation as a sonographic marker to screen for congenital heart defects (CHD). METHODS This is a multi-center retrospective study in which singleton gestations of euploid fetuses were analyzed. NT measurement was performed in the first trimester examination when the fetal crown-rum...

Objective We sought to assess blood fl ow in relation to jugular lymphatic distension in fetuses with increased and normal nuchal translucency (NT). Study design In all, 72 fetuses with normal NT and 71 fetuses with NT > 95th percentile were evaluated. NTsize, jugular lymphatic sacs (JLS), jugular vein and ductus venosus pulsatility index for veins (PIV), and intracardiac velocities were measur...

AIMS To establish the normative data distribution of nuchal translucency (NT) thickness in Thai fetuses. METHODS A cross-sectional multicenter study was conducted among 6,455 women with singleton pregnancies and gestational age between 10 and 14 weeks. For each case, the fetal crown-rump length (CRL) and NT were measured by transabdominal ultrasound. Transvaginal ultrasounds were used in poor...

OBJECTIVE Nuchal translucency (NT) seen ultrasonographically at 11-14 weeks' gestation is a sensitive marker for Down syndrome. Despite its important role for Down syndrome screening, its use is still considered controversial due to high false-positive rates. We speculated that progesterone could lead to abnormal blood flow patterns and, subsequently, to increased NT. Our primary endpoint was t...

Sonographic assessment of nuchal translucency (NT) thickness has been recognized as an effective means of screening for trisomy 21 and other chromosomal abnormalities at 11–14 weeks of gestation. Up to 80% of aneuploid fetuses have increased NT, but this feature is also found in 5% of karyotypically normal fetuses at this stage of pregnancy (Snijders et al., 1998). As this screening test examin...

BACKGROUND To investigate normal reference values of nuchal translucency (NT) thickness in normal Taiwanese fetuses between 11 and 14 weeks of gestation. METHODS A prospective study of ultrasound measurements of fetal NT and crown-rump length (CRL) at 11-14 weeks of gestation was conducted in 724 consecutive Taiwanese fetuses between 1998 and 2001. The relationship between NT and 5-mm interva...