نتایج جستجو برای: intracoronary brach therapy
تعداد نتایج: 657554 فیلتر نتایج به سال:
BACKGROUND We analyzed in the present study the influence of intracoronary autologous freshly isolated bone marrow cells transplantation (BMCs-Tx) on cardiac function in patients with acute myocardial infarction (AMI). METHODS AND RESULTS The 32 patients with AMI were enrolled in this prospective nonrandomized study to either freshly isolated BMC-Tx or to a control group without cell therapy....
Differential effects of natriuretic peptides and NO on LV function in heart failure and normal dogs.
beta-Adrenergic hyporesponsiveness in congestive heart failure (CHF) is mediated, in part, by nitric oxide (NO). NO and brain natriuretic peptide (BNP) share cGMP as a second messenger. Left ventricular (LV) function and inotropic response to intravenous dobutamine (Dob) were assessed during sequential intracoronary infusion of saline, HS-142-1 (a BNP receptor antagonist), and HS-142-1 + N(G)-m...
BACKGROUND In patients with acute myocardial infarction or unstable angina undergoing coronary angioplasty, abciximab reduces major adverse cardiac events (MACE). Clinical trials have studied intravenous administration only. Intracoronary bolus application of abciximab causes very high local drug concentrations and may be more effective. We studied whether intracoronary bolus administration of ...
Intravascular Ultrasound(IVUS) is an imaging technology which provides cross-sectional images of internal coronary vessel structures. The IVUS frames are acquired by pulling the catheter back with a motor running at a constant speed. However, during the pullback, some artifacts occur due to the beating heart. These artifacts cause inaccurate measurements for total vessel and lumen volume and li...
Zusammenfassung Das sozialistische Wirtschaftssystem der DDR brach 1990 zusammen. Nach Wiedervereinigung war es das Kernziel des Aufbaus Ost, einen Wirtschaftssektor in Ostdeutschland (der ehemaligen DDR) zu schaffen, im internationalen Wettbewerb bestehen kann. Die sozialistischen Betriebe wurden privatisiert oder geschlossen. Der Staat hat Investitionen durch Subventionen massiv gefördert. he...
RATIONALE The Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease (CUPID 1) study was a phase 1/phase 2 first-in-human clinical gene therapy trial using an adeno-associated virus serotype 1 (AAV1) vector carrying the sarcoplasmic reticulum calcium ATPase gene (AAV1/SERCA2a) in patients with advanced heart failure. The study explored potential benefits of the ...
In just a few years, research into the use of stem cells for treating patients with acute myocardial infarction has become a reality in Spain. Since the first safety studies we have moved on to the design of randomized trials to determine whether this therapy works. To understand why the paper by Suárez de Lezo et al1 deserves to be discussed in an editorial, the short history of cell therapy i...
Autologous bone marrow cell transplantation (BMCs-Tx) is a promising novel option for treatment of cardiovascular disease. We analysed in a randomized controlled study the influence of the intracoronary autologous freshly isolated BMCs-Tx on the mobilization of bone marrow-derived circulating progenitor cells (BM-CPCs) in patients with acute myocardial infarction (AMI). Sixty-two patients with ...
BACKGROUND Mesenchymal stem/stromal cells have unique properties favorable to their use in clinical practice and have been studied for cardiac repair. However, these cells are larger than coronary microvessels and there is controversy about the risk of embolization and microinfarctions, which could jeopardize the safety and efficacy of intracoronary route for their delivery. The index of microc...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید