Six adult dairy cows clinically diagnosed as hemorrhagic bowel syndrome (HBS) were the subjects of this study. The involved intestinal lesions were fixed in formalin and examined macroscopically and histopathologically. Pathological examinations revealed large intramural hematomas with necrotic foci, resulting in luminal obstruction. The mucosal layer in the lesions was detached from the intest...

Activated polymorphonuclear leucocytes, which are accumulated in inflammatory lesions of inflammatory bowel disease, produce tissue destructive, oxygen derived free radicals and other inflammatory mediators. The PMN superoxide production elicited by formyl-methionyl-leucyl-phenylalanine or the complement split product 5a were compared in IBD and healthy volunteers. Significantly reduced superox...

BACKGROUND Complex cartilage lesions of the knee including large cartilage defects, kissing lesions, and osteoarthritis (OA) represent a common problem in orthopaedic surgery and a challenging task for the orthopaedic surgeon. As there is only limited data, we performed a prospective clinical study to investigate the benefit of autologous chondrocyte implantation (ACI) for this demanding patien...

PURPOSE To evaluate the negative predictive value (NPV) of ultrasound (US) elastography for non-palpable Breast Imaging Reporting and Data System (BI-RADS) category 3 lesions on ultrasonography and to determine whether US elastography is helpful in reducing the number of BI-RADS category 3 lesions on ultrasonography. METHODS Two hundred seventy-six consecutive, non-palpable BI-RADS category 3...

Results Histology was positive for high-grade cancer in 27/50 patients. Lesions deemed to be suspicious for cancer (PI-RADS score 4 and 5) had a positive predictive value of 83% (25/30), and were located correctly in 88%. Lesions deemed to be benign (PI-RADS score 1/2) had a negative predictive value of 80% (8/10). Equivocal lesions (PI-RADS score 3) were histologically higher grade (Gleason 3+...

A lethal enterocolitis was induced in hamsters by oral or parenteral administration of clindamycin in amounts comparable to those used in treatment of humans. The intestinal lesions were characterized histologically as an acute inflammatory reaction with pseudomembrane formation and resembled the lesions seen in humans with antibiotic-induced colitis. Results of quantitative stool cultures show...

The lengthy and tortuous journey, the unstable positioning of the colon and rectum, and variations in intestinal wall thickness during intestinal peristalsis have brought about significant difficulties for computed tomography (CT) diagnosis. Glucose metabolism is unstable in the colon and rectum, and smooth muscle peristalsis, gland secretion, spasms, and inflammation can also cause abnormal me...