نتایج جستجو برای: international classification of retinoblastoma
تعداد نتایج: 21223292 فیلتر نتایج به سال:
Retinoblastoma patients have cellular and humoral reactivity towards antigens expressed on retinoblastoma cells. We report the ultrastructural, cytogenetic, and immunologic features of four new retinoblastoma derived tissue culture cell lines. Studies with hybridoma produced monoclonal antibodies demonstrate that these lines share antigens with a previously described long-term allogeneic retino...
A registry including information about nearly 1,600 cases of retinoblastoma diagnosed in Britain has been created at the Childhood Cancer Research Group. Cases have been classified as 'old germ cell mutation', 'new germ cell mutation' or 'sporadic non-hereditary'. For a population-based group of 918 cases diagnosed between 1962 and 1985 we have calculated the proportions of unilateral/bilateral...
PURPOSE Perturbations in the retinoblastoma pathway are over-represented in advanced prostate cancer; retinoblastoma loss promotes bypass of first-line hormone therapy. Conversely, preliminary studies suggested that retinoblastoma-deficient tumors may become sensitized to a subset of DNA-damaging agents. Here, the molecular and in vivo consequence of retinoblastoma status was analyzed in models...
OBJECTIVE Optimal care in RA includes early use of DMARDs to prevent joint damage and hopefully decrease the need for costly surgical interventions. Our objective was to determine whether a reduced rate of orthopaedic surgery was evident for persons with RA who saw a rheumatologist early in the disease course. METHODS We studied persons who had a diagnosis of RA based on billing code data in ...
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted therapies available. This is, in part, due to the lack of highly penetrant and rapid retinoblastoma animal models that facilitate rapid identif...
this study investigates the relationship between market structure and profitability in the iranian manufacturing industries. in this study, raw data based on international standard industrial classification (at four digit code) has been used. fixed effects panel estimation method (based on diagnostic test results) has been chosen for empirical investigation. the result of the study confirms the...
Retinoblastoma is a rare childhood cancer of the retina that begins in utero and is diagnosed in the first years of life. The goals of retinoblastoma treatment are ocular salvage, vision preservation, and reduction of short- and long-term side effects without risking mortality because of tumor dissemination. To identify better chemotherapeutic combinations for the treatment of retinoblastoma, s...
Iran’s proper status in the development of science and knowledge at the international level represents the institutionalized decision making system in this sector of the country. Besides, Iran’s strategic documents always emphasize on the formation of a place for the country’s knowledge and technology. Regarding to the development of technologies and IT infrastructures, this paper focuses the t...
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