The following is the case of a man aged 61 with a history of smoking and laryngeal papillomatosis. He was treated with multiple endoscopic surgical interventions. Transformation to stage III larynx and neck (T3, N1) cancer was presented and a total laryngectomy was performed with bilateral neck dissection and left internal jugular vein (IJV) ligation. The anatomopathological report showed epide...

OBJECTIVE To define the optimal treatment for women with stage III or locally advanced breast cancer (LABC). EVIDENCE Systematic review of English-language literature retrieved from MEDLINE (1984 to June 2002) and CANCERLIT (1983 to June 2002). A nonsystematic review of the literature was continued through December 2003. RECOMMENDATIONS The management of LABC requires a combined modality tr...

variation of the branches of the external carotid artery (eca) is well known, but it is extremely rare for the occipital artery (oa) to arise from the internal carotid artery (ica). a 87-year-old man was found to have this anatomical variation on the right side by threedimensional computed tomography angiography for vascular mapping of the carotid arteries before superselective intra-arterial c...

Microvascular free tissue transfer in head and neck reconstruction requires suitable recipient vessels, which are frequently compromised by prior surgery, radiotherapy, or size of the tumour. A surgical description of an arterial free flap pedicle anastomosis on the reverse internal carotid arterial flow in a vessel-depleted neck is presented. A 66-year-old male with a relapse of hypopharyngeal...

A 62-year-old man underwent radiotherapy to the left upper chest for treatment of Pancoast syndrome on a background of previous coronary artery bypass grafting 12 years earlier. Within 1 year, he developed significant stenoses of both the left internal mammary artery (LIMA) graft and ostial left vertebral artery, presumably related to therapeutic radiation exposure. Initially diagnosed using co...

This review describes strategies for the delivery of therapeutic radionuclides to tumor sites. Therapeutic approaches are summarized in terms of tumor location in the body, and tumor morphology. These determine the radionuclides of choice for suggested targeting ligands, and the type of delivery carriers. This review is not exhaustive in examples of radionuclide carriers for targeted cancer the...

introcduction: pigmented villonodular synovitis (pvs) is rare, benign and proliferative disorder of synovium which consists of villous and/ or nodular formations in joints.diagnosis is determined by clinical features, aspiration of the joint, radiographic features and magnetic resonance imaging (mri).the definitive treatment is the complete resection of affected tissue by open or arthroscopic s...

background: mucositis is an important adverse effect of cancer treatment. the aim of this study was to investigate the effect of ice cubes on oral mucositis following head and neck radiotherapy. materials and methods: a randomized controlled trial was conducted on 40 head and neck cancer patients who underwent radiotherapy. the patients were randomly divided into two experimental and control gr...

background: acute radiation dermatitis is a very common side effect of radiation therapy in large numbers of cancers including breast cancer. despite high prevalence rate of acute radiation dermatitis and also wet desquamation, a few trials on prophylaxis of this complication using topical treatment have been conducted. despite effectiveness of topical corticosteroids in treatment of acute radi...

introduction accurate estimation of the absorbed dose in radiosensitive organs, located away from the target volume during radiotherapy, is one of the main reasons for the development of reference phantoms. the international commission on radiological protection (icrp) reference phantoms can provide a more realistic view of the human anatomy in comparison with the previously used mathematical p...