نتایج جستجو برای: interleukin 28b polymorphism
تعداد نتایج: 201199 فیلتر نتایج به سال:
Background and Objective: Genetic factors greatly impact the response to treatment in patients. Recent studies on rs10853728 single nucleotide polymorphisms in the promoter area, determined the IL-28B gene as a host factor affecting the treatment of hepatitis C infection. The aim of this study was to evaluate this polymorphism among Iranian patients Materials and Methods: This cross-sectiona...
Introduction: Helicobacter pylori is the main cause of chronic inflammation and peptic ulcer. More than half of the world population is afflicted with Helicobacter, while only 20% of people show the clinical symptoms of the disease. Genes encoding the cytokines interleukin (IL)-1B play a key role in the inflammatory responses of gastric mucus. This study aims to analyze polymorphism in the IL-1...
introduction: hepatitis b is a potentially life-threatening infection that causes acute infection and chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma (hcc). interleukin-12 (il12) is responsible for activation of th1 immune responses, leading to possible clearance of hbv infection from the host’s body. the host’s immune-genetic background plays an important role in t...
Background& Objective: Host resistance towards Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. According to the important role of IL-13 in the defense against visceral leishmaniasis (VL) and the known effect of the IL-13 gene polymorphisms on its production, the aim of this study was to investigate the probable relationship be...
Permeability of rainbow trout gill pavement cells cultured on permeable supports (single seeded inserts) changes upon exposure to freshwater or treatment with cortisol. The molecular components of this change are largely unknown, but tight junctions that regulate the paracellular pathway are prime candidates in this adaptational process. Using differential display polymerase chain reaction we f...
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