Dear Editor: Suicide is the ninth leading cause of death in the US and the third leading cause for Americans aged 15 to 24 years (1). In Canada, suicide rates are higher (2). Fetal alcohol spectrum disorders (FASD) are common and preventable developmental disabilities with a prevalence of 1 in 100 (3). Previous reports suggest that individuals with FASD are at risk for suicide (4,5). An individ...

Children suffering from intellectual deficiency and disorders arising from such a condition tend to be provided with a specific form of education, depending on the deficiency type and degree. Apart from the disorder itself, the acquisition of knowledge, skills and learning habits depends on the children’s motivation for learning, as well as the accessibility of the computer. When used in confor...

BACKGROUND Four cases of paroxysmal kinesigenic dyskinesia (PKD) have been reported in individuals with proximal 16p11.2 microdeletions that include PRRT2. CASE REPORT We describe a fifth patient with PKD, features of Asperger's syndrome, and mild language delays. Sanger sequencing of the PRRT2 gene did not identify any mutations implicated in PKD. However, microarray-based comparative genomi...

According to ICD – 10 (1993) there are two big groups of specific developmental disabilities: learning disabilities and motor disabilities. The first includes a group of disorders which characterize problems in school achievement, especially in reading and math. The second includes a group of disorders in motor coordination, balance, lateralization, which cannot be explained by general problems...

Patient Selection Criteria Coverage eligibility will be considered for fragile X mental retardation 1 (FMR1) mutations the following patient populations:  Individuals of either sex with intellectual disability, developmental delay, or autism spectrum disorder (see Policy Guidelines ◊ ).  Prenatal testing of fetuses of known carrier mothers (see Policy Guidelines ◊ ).  Affected individuals or...

Chromosomal microarray analysis (CMA) testing has been proposed for detection of genetic imbalances in infants or children with characteristics of developmental delay/intellectual disability (DD/ID), autism spectrum disorder (ASD), and/or congenital anomalies. CMA increases the diagnostic yield over karyotyping in this population and may impact clinical management decisions. Next-generation seq...

Despite increased awareness and concern about children with developmental disabilities wandering away from adult supervision, there is a paucity of research about elopement. This is the first study to examine and report the prevalence and correlates of elopement in a nationally representative sample of school-age children in the United States with an autism spectrum disorder (ASD) and/or cognit...

Description: Chromosomal microarray (CMA) testing has been proposed for detection of genetic imbalances in infants or children with characteristics of developmental delay/intellectual disability or autism spectrum disorder. G-banded karyotyping has for many years been the standard first-line test for this purpose. G-banded karyotyping allows visualization and analysis of chromosomes for chromos...