Alternative splicing choices are governed by splicing regulatory protein interactions with splicing silencer and enhancer elements present in the pre-mRNA. However, the prediction of these choices from genomic sequence is difficult, in part because the regulators can act as either enhancers or silencers. A recent study describes how for a particular neuronal splicing regulatory protein, Nova, t...

Int. J. Adv. Engg. Res. Studies/III/I/Oct.-Dec.,2013/58-60 Review Article EVALUATING THE DESIGN OF AN AUTOMOBILE SILENCER THROUGH FEA METHODOLOGY FOR MINIMIZING THE VIBRATIONS GENERATED DURING ITS OPERATION 1 Kaushik Ramchandra Gadre, 2 T. A. Jadhav, 3 Swapnil S. Kulkarni Address for Correspondence 1 ME-Mech/Design (pursuing), 2 Associate Prof., Sinhagad College of Engineering, Pune 3 Director-...

The addition of racing exhaust to a vehicle will greatly affect the quality emissions. Racing exhausts that use FreeFlow system which throws remaining combustion gases out immediately without any deflection and catalyst in exhaust. DB Killer uses nest-shaped copper material, besides reducing noise it also reduces excessive emissions material is easy obtain, inexpensive, has simple manufacturing...

the starting behavior of a supersonic axisymmetric mixed compression air intake was numerically investigated. the code solves reynolds-averaged navier–stokes equations using an explicit finite volume method in a structured grid by the roe flux difference splitting scheme. further, it uses the baldwin–lomax algebraic model to compute the turbulent viscosity coefficient. the correct method of sur...

Active and silenced chromatin domains are often in close juxtaposition to one another, and enhancer and silencer elements operate over large distances to regulate the genes in these domains. The lack of promiscuity in the function of these elements suggests that active mechanisms exist to restrict their activity. Insulators are DNA elements that restrict the effects of long-range regulatory ele...