نتایج جستجو برای: insulin
تعداد نتایج: 183217 فیلتر نتایج به سال:
Insulin is essential for type 1 and advanced type 2 diabetes to maintain blood glucose levels and increase the patient’s longevity. Frequent subcutaneous insulin injections are usually associated with pain, local tissue necrosis, infection and nerve damage. Recently, a number of new delivery methods such as oral insulin delivery have been developed to overcome these limitations and increase pa...
Background: Polycystic ovarian syndrome (PCOS) is a multifactorial endocrine disorder which along with insulin resistance leads to infertility and metabolic (MetS). This increases the cardiovascular risk in PCOS patients. Aims Objectives: The study was undertaken objective assess compare levels of insulin, HOMA IR, lipoprotein (a), comprehensive lipid tetrad index (CTLI) patients andwithout Met...
In this study, N,N-Dimethyl-N-Octyl chitosan was synthesized. Nanoparticles containing insulin were prepared using PEC method and were statistically optimized using the Box-Behnken response surface methodology. The independent factors were considered to be the insulin concentration, concentration and pH of the polymer solution, while the dependent factors were characterized as the size, zeta po...
In order to investigate the relationship between insulin to glucagon ratio and metabolic factors in transitional period of dairy cows, 28 cows heifers with body condition score of 3.25- 3.75 were selected. Dairy cows received close up diet, from 21 days prepartum until parturition and lactation diet according to nutritional requirements after parturition. Blood was sampled at 10 days before and...
ABSTRACT Introduction: Apelin and resistin as novel adipokines have insulin-sensitizing effects, which may be associated with decreased blood glucose concentration. In this study, we aimed to investigate the impact of combined exercise training on plasma concentrations of apelin, resistin and insulin resistance in patients with type 2 diabetics male (T2D). Methods: In a quasi-...
Background: Although effects of trace elements on secretion of sex steroids and insulin have been studied, the effects of these hormones on serum level of trace elements have been rarely investigated. The aim of the present study was to evaluate the effect of testosterone and finasteride administration and castration on serum levels of testosterone, insulin, zinc and chromium. Methods: Male adu...
Background and Aim: Selective PDE3 inhibitors, via cyclic adenosine monophosphate (cAMP) accumulation increase cardiac contraction and augment glucose-induced insulin secretion. In this study, the effects of some synthetic methylquinolinone derivatives (MC1-MC10) on glucose-induced insulin secretion in rats' isolated Langerhans islets model were investigated. Materials and Methods: After...
Introdution: Adiponectin is a peptide secreted from fat cells that plays an important role in the development of insulin resistance and type 2 diabetes. A number of single nucleotide polymorphisms in the adiponectin gene are associated with lower adiponectin expression and T2DM. The aim of this study was to determination the frequency of rs 2241766 polymorphism in adiponectin gene and its relat...
Objective(s): Diabetes can gradually cause damage to the function and structure of male gonads. This survey was conducted to investigate the effect of troxerutin on hormonal changes, serum oxidative stress indices, and testicular function and structure in prepubertal diabetic rats.Materials and Methods: Fifty prepubertal (6 weeks old) male Wistar rats were divided into five groups including Con...
Background: There is not any in vivo studies that shows inducing of euglycemia by vanadyl is independent from plasma insulin. Therefore in the present study we planned to investigate the antidiabetic effects of vanadyl in diabetic rats. Materials and Methods: Rats became severely diabetic by an IV injection of 50-55mg/kg streptozotocin (STZ), 15 days after the injection, the blood glucose of ...
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