whereby each system design is closely related to the kind of tasks it should support. The focus in designing the Shiftplanassistant, a system for the design of shift rotas as described in (Gärtner 1995), was on developing tools that support professional shift rota designers in accomplishing their task. The system eases the construction of rotas and allows at the same time for high flexibility i...

Hepatitis C virus (HCV) isolates have been classified into six main genotypes. Genotyping methods, and especially the widely used line probe assay (LiPA), are frequently based on the 5'-untranslated region (5'UTR). However, this region is not appropriate for discriminating HCV strains at the subtype level and for distinguishing many genotype 6 samples from genotype 1. We investigated the capaci...

Human papillomavirus (HPV) DNA genotyping is an essential test to establish efficacy in HPV vaccine clinical trials and HPV prevalence in natural history studies. A number of HPV DNA genotyping methods have been cited in the literature, but the comparability of the outcomes from the different methods has not been well characterized. Clinically, cytology is used to establish possible HPV infecti...

Background. Occult hepatitis C virus infection (OCI) was identified as a new form of Hepatitis C virus (HCV), characterized by undetectable HCV antibodies and HCV RNA in serum, while HCV RNA is detectable in liver and peripheral blood cells only. Aim. The aim of this study was to investigate the occurrence of OCI in Egyptian patients with lymphoproliferative disorders (LPDs) and to compare its ...

BACKGROUND To examine the relationship between human papillomavirus (HPV) and giant cell arteritis (GCA) of the temporal artery. METHODS The study group consisted of 22 cases of histologically positive/biopsy confirmed GCA. The control groups consisted of 21 histologically negative temporal artery biopsies and fifteen cases of vascular margins of nephrectomies. For detection of the presence o...

Pain in the chest is quite frequently the Presenting symptom in cases of heart disease. Little importance was however attached to this symptom till 1786, when Heberden presented the medical profession with a masterly description of angina pectoris. Since that time, much has been written, mainly of a controversial Mature, on the aetiology, diagnosis and treatment anginal pain. The passage of tim...