Abstract Background and Aims Kidney injury molecule 1 (KIM-1) is a transmembrane glycoprotein expressed by proximal tubular cells, recognized as an early, sensitive, specific urinary biomarker for kidney injury. Blood KIM-1 was recently associated with the severity of acute chronic damage but its value in ANCA-associated vasculitis glomerulonephritis (ANCA-GN) has not been studied. Thus, we ana...

spinal cord injury (sci) in humans remains a devastating and incurable disorder. a very important obstacle in axonal regeneration after spinal cord injury is astroglial scaring. the use of self-assembling peptide nanofiber, a hydrogel mimicking extracellular matrix, has been suggested as a scaffold for spinal cord regeneration and inhibition of astrogliosis. however, neurogenesis potential of l...

traumatic brain injury resulting road accidents create damage to the brain. the severe brain injury may cause extensive tissue loss of several parenchyma which results in cavities due to primary destruction and secondary injuries such as ischemia and inflammation. recent findings suggest that neuronal precursors in the adult mammalian brain can be a therapeutic target in ischemic brain injuries...

traumatic brain injury (tbi) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. the use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of tbi. in the present study, we surveyed the beneficial effec...

rehabilitation is the ongoing management of injuries and disabilities after an accident. it will help people to maximize the individuals` recovery through the relearning of skills or teaching of strategies to compensate for changed abilities. self-esteem may be one major factor related to the manner in which people with spinal cord injury (sci) respond to rehabilitation. following a short discu...

conclusions more than half of the patients were disabled after 3 months of trauma. elderly patients, patient with severe trauma, and long hospitalization and patients with extremity injuries were high risk for disability. results the mean disability scores at 1 and 3 months post-injury was 30.3 (9.2) and 18.8 (8.3), respectively and there was a statistical significant difference between disabil...

Since the emergence of novel coronavirus 2019 disease (COVID-19), cardiovascular impairment and alterations in cardiology laboratory tests suggestive myocardial injury, even patients without symptoms, have been observed hospitalized children adults.– Epidemiological data from China suggested that cardiac injury may occur 19% to 28% with COVID-19. Several factors seem contribute damage, potentia...

back ground  subsequent to spinal cord injury many pathological changes may occur that could lead to inappropriate environment for repair. the most important of such changes is the death of neurons. exogenous administration of growth factors that modulate neuronal survival, synaptic plasticity, and neurotransmission has been proposed as a potential therapeutic treatment for sci. among these gro...

The journal retracts the article “A Potential Role of Apelin-13 against Hepatic Injury and Metabolic Disorders in Preeclampsia Induced by L-NAME [...]