This briefing paper uses five case studies of health economies in the English NHS as a basis for examining how local clinicians and managers are working together to develop closer service integration and less fragmented care for patients. It focuses on what is facilitating or impeding change and sets out proposals for policy-makers that are designed to enable more rapid progress towards develop...

The potential of open data as a resource for driving citizen-led urban innovation relies not only on a suitable technical infrastructure but also on the skills and knowledge of the citizens themselves. This paper describes how a smart city project in Milton Keynes, UK, is supporting multiple stages of citizen innovation, from ideation through to citizen-led smart city projects. This approach en...

In this article, the author argues that there are psychological and biological constraints on our moral behaviour, rational decision-making and capacities to love. For example, low oxytocin levels can constrain our willingness to cooperate with others, and our capacity to maintain long-term loving relationships. There is also evidence that increasing iodine intake can improve a person's general...

Many postnatal onset neurological disorders such as autism spectrum disorders (ASDs) and intellectual disability are thought to arise largely from disruption of excitatory/inhibitory homeostasis. Although mouse models of Rett syndrome (RTT), a postnatal neurological disorder caused by loss-of-function mutations in MECP2, display impaired excitatory neurotransmission, the RTT phenotype can be la...

In recent years a large number of identity management systems have been proposed. Unfortunately, although these systems offer the possibility of significantly improving user security, they have not been widely adopted, typically because the cost of adoption is too high for the involved parties. In this talk we consider the problem of designing identity management systems which offer security ad...