The effect of intraperitoneal injections of dipyridamole on the elevations of intraocular pressure and anterior chamber aqueous humor protein produced by topical application of prostaglandin E2 was studied in rabbits. Pretreatment with 100 mg/kg dipyridamole inhibited the prostaglandin E2--induced ocular hypertension and rise of aqueous humor protein. Systemic administration of dipyridamole did...

PURPOSE To assess current practice patterns for dry eye patients in South Korea and to evaluate the preference according to the ages and clinic types of physicians. METHODS Dry eye patients (n = 1,612) were enrolled in this multicenter cross-sectional, observational study. The severity level of dry eye patients was classified based on the Korean guidelines for dry eye treatment. The medical r...

A 47-year-old man presented at the Ophthalmology Department of Saku City Asama General Hospital complaining of hyperemia and pain after industrial sodium hydroxide (approx. 40% concentration) had entered his left eye. With an epithelial defect of the bulbar and palpebral conjunctiva, ischemia of the inferior third of the limbal conjunctiva, a total corneal epithelial defect and mild corneal str...

Previous papers examined lipid peroxidase levels and myeloperoxidase activity as products of oxidative and inflammatory reactions in the tear fluid of patients suffering from dry eye. The aim of the present paper was to investigate whether the enzymes xanthine oxidoreductase/xanthine oxidase known to generate reactive oxygen species contribute to oxidative reactions on the ocular surface. Xanth...

The review presents data from studies of the ophthalmological consequences disease caused by SARS-CoV-2, especially regarding its rare manifestations. Clinical manifestations post-COVID-19 syndrome disappear within about two weeks in mild cases and 3 to 12 more severe cases. 80 % patients have than one, often two, 10 symptoms. In general, improve spontaneously continuously over time. ophthalmic...

Ocular inflammation has become a hot topic in ophthal-mology, involving also several areas of medicine: internal optic nerve. Management of ocular inflammation presents diagnostic and therapeutic challenges, ranging the etiology and prognosis from benign, self-limited conditions to organ-threatening disorders. Ocular inflammation is a component of eye surgery, sometimes leading to its complicat...

OBJECTIVE To determine whether blocking prolymphangiogenic factors such as vascular endothelial growth factor C (VEGF-C) would suppress alloimmunity in dry eye disease using a murine model. METHODS The effects of intraperitoneal injections of 400 μg of anti-VEGF-C antibody (treated group) and intraperitoneal normal saline (untreated group) were studied in murine dry eyes induced by exposing m...

Dry eye disease (DED) is one of the most common conditions encountered by ophthalmologists in their practice. Currently, experts consider meibomian gland dysfunction to be leading cause dry syndrome. This condition characterized obstruction discharge ducts and/or changes glandular secretion, which leads disturbance tear film stability and provokes inflammatory process ocular surface. The purpos...

Birdshot retinochoroidopathy is a rare inflammatory eye disease with typical clinical presentation and strong association with the HLA-A29 allele. Characteristic appearances on fluorescein angiogram (FA), indocyanine green (ICG) angiography, and electroretinogram (ERG) have been described. However, histopathology of the disease has been rare. 3 The following case is an example of birdshot retin...