introduction: knee osteoarthrosis is one of the most debilitating diseases. prolotherapy includes intraarticular injection of various drugs to decrease inflammation. injection of intradiscal o2-o3 has reduced pain and disability of patients with low back pain due to prolapsed lumbar disk. objective: to compare the effect of intraarticular injection of ozone and steroids in improvement of clinic...

background : there is an association   of celiac disease (cd) with several gastrointestinal illnesses. we aimed to determine   the prevalence of cd in patients with inflammatory bowel disease (ibd) to evaluate the value of the routine serological tests for cd in these patients. methods : patients with ibd underwent   screening test for cd. the screening test was based on iga anti-ttg antibody e...

conclusions exercise can improve anthropometric variables, body composition and vo2 peak and reduce some inflammatory markers in breast cancer survivors. objectives the current study aimed to investigate the effect of eight weeks of training on il-6, tnf-α and hcrp in postmenopausal breast cancer survivors. patients and methods twenty-seven postmenopausal breast cancer survivors with mean age o...

Rheumatoid arthritis (RA) is an inflammatory disease that utilizes nonbiologic and biologic drugs for appropriate management. However, high cost, adverse effects, reduced effectiveness, risk of infection have stimulated the search safer more efficacious therapeutic strategies. In present study, we aimed to evaluate anti-inflammatory analgesic properties eucalyptol in experimental model arthriti...

Sphingolipids (SLs) are essential structural components of mammalian cell membranes. Our group recently determined that the oral anaerobe Porphyromonas gingivalis delivers its SLs to host cells and ability P. synthesize limits elicited inflammatory response during cellular infection.

leptadenia reticulata was reported to be used for several medicinal purposes. the present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of l. reticulata. the anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. pro inflammatory mediators (il2, il6, tnf-α) in serum of treated and control organism ...

Autochthonous strains belonging to Lacticaseibacillus paracasei and casei were screened based on pro-technological (kinetics of growth acidification, exopolysaccharides biosynthesis), functional (cell viability during processing storage, in vitro protein digestibility, gastrointestinal batch digestion), sensory properties ferment milk intended be included the ice-cream formulation. The main dis...

The ability to block specific cytokine pathways has revealed pathophysiological differences among autoimmune diseases (e.g., the efficacy of TNF inhibitors in arthritides and inflammatory bowel disorders their inefficacy giant-cell arteritis multiple sclerosis), providing a framework for reclassification.