Inflammatory Bowel Disease (IBD) is common in most industrialised countries and childhood IBD accounts for nearly 30% of total cases. Various studies, mostly from Europe and USA have reported epidemiological characteristics of childhood IBD. The incidence figures vary greatly from region to region and within a region over time. Almost all reported studies have documented an increase in the inci...

Rheumatic manifestations, in particular joint complaints, are frequent features in inflammatory bowel disease (IBD), with a prevalence varying from 10 to 35%. Their spectrum is almost wide, involving bone, tendons, entheses and joints. Joint manifestations may be seen as arthralgia and/or inflammatory arthropathies. These latter may in turn be found in three principal forms: the peripheral, the...

Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, are disabling conditions characterised by chronic, relapsing inflammation of the gastrointestinal tract. Current treatments are not universally effective or, in the case of therapeutic antibodies, are hampered by immune responses. Janus kinase inhibitors are orally delivered small molecules that target cytokine signall...

BACKGROUND Endoscopy is an essential diagnostic and therapeutic modality in the clinical care of inflammatory bowel disease (IBD) patients. Endoscopic therapy can be used for treatment of disease-related strictures, surveillance and resection of intraepithelial neoplasia, and treatment of fistulas or disease-related complications, and is currently being evaluated regarding its capacity in in vi...

Inflammatory bowel disease (IBD) is a chronic systemic disorder, which mainly affects the bowel. However, both ulcerative colitis (UC) and Crohn’s disease (CD) are often associated with extra intestinal manifestations, complications, and other autoimmune disorders. These manifestations can involve almost any organ system, including the musculoskeletal, dermatologic, hepatopancreatobiliary, ocul...

INTRODUCTION Inflammatory bowel disease is a chronic condition of the gastrointestinal tract, comprising mainly Crohn disease (CD) and ulcerative colitis (UC). Both of them are frequently encountered in children, being multifactorial conditions, with an unclear etiology. PATIENTS CONCERNS We present 4 cases of inflammatory bowel disease (IBD) in children in order to underline the variable evo...

Inflammatory Bowel Diseases - ulcerative colitis and Crohn's disease- are chronic gastrointestinal inflammatory diseases of unknown etiology. Decreased oral intake, malabsorption, accelerated nutrient losses, increased requirements, and drug-nutrient interactions cause nutritional and functional deficiencies that require proper correction by nutritional therapy. The goals of the different forms...

inflammatory bowel disease (ibd) is an irregular response of immune system accompanied with different inflammatory manifestations including alterations in cytokines. probiotics are non-pathogenic organisms with probable effects in various conditions such as inflammation. the present study hypothesized whether oral intake of bifidobacterium and lactobacillus in form of probiotic yogurt may repre...

the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

background the incidence of inflammatory bowel disease (ibd) varies among different societies. the aim of this study is to determine the incidence rate of ibd in kerman, a city in southeast iran. methods all medical records that indicated a new diagnosis of ulcerative colitis (uc) or crohn`s disease (cd) were retrieved from the gastrointestinal endoscopy and pathology departments of 12 centers ...