Approximately 15% of couples in the reproductive age group worldwide are affected by infertility, and it is estimated that about 40-50% of infertilities are of male origin. Genetic factor accounts for 10-15% of severe male infertility, including chromosomal aberrations and single gene mutations (Ferlin et al, 2006). After the Klinfelter syndrome, Y chromosomal microdeletions are the most freque...

Background: Every human being, especially a married couple, wants children. Obstacles to obtaining children are called infertility. One of the Assisted Reproductive Technology (ART) procedures used for treating infertility is intrauterine insemination (IUI), non-invasive procedure with affordable costs. The success IUI influenced by many factors, one which sperm agglutination.
 Objective: ...

Approximately 10 to 15% of couples are impacted by infertility. Recently, the pivotal role that lifestyle factors play in the development of infertility has generated a considerable amount of interest. Lifestyle factors are the modifiable habits and ways of life that can greatly influence overall health and well-being, including fertility. Many lifestyle factors such as the age at which to star...

Infertility associated with anovulation is a well recognised ootity but recently disturbed ovulation, early or delayed, accompanied with the luteal phase defect has been considered pathological as it leads to sterility or ear1y miscarriages. (Gillam, 1955; Grant, et al, 1959; Jones and Purmand, 1962; Israel, 1967, and Arrata, and Iffy, 1971). Thus, detection as well as dating the ovulation is e...

It has recently been reported that vitamin D blood plasma levels are associated with reduced risk of endometriosis. The present study aimed to investigate whether the vitamin D binding protein (GC), vitamin D receptor (VDR), and retinoid X receptor (RXR) gene variants may be genetic risk factors for endometriosis‑associated infertility. The subjects consisted of 154 women with endometriosis‑ass...

BACKGROUND Pelvic infection, unsafe abortion and previous laparatomy are risk factors for tubal infertility among Nigerian women. Reports on the relationship between these factors and tubal pathology seen on hysterosalpingography (HSG) from our environment have been few. OBJECTIVE To assess the prevalence of tubal occlusions among patients referred for HSG and examine the association between ...

Infertility is a complex pathophysiological condition. It may caused by specific or multiple physical and physiological factors, including abnormalities in homeostasis, hormonal imbalances and genetic alterations. In recent times various studies implicated that, aberrant epigenetic mechanisms are associated with reproductive infertility. There might be transgenerational effects associated with ...

BACKGROUND Secondary infertility in developing countries is mostly attributable to blockage of the fallopian tubes due to adhesions caused by reproductive tract infections. There is a dearth of information on the prevalence and causes of secondary infertility from Pakistan. This paper presents results on factors associated with secondary infertility among married women in Karachi, Pakistan. M...

Infertility is a growing medical and social problem in the world; and approximately one of five couples has problems with conception [1]. Several fertility workers did focus in their search on female etiological factors for infertility, despite the fact that assessment of male fertility potential is of great importance. Male partner may involve in the aetiology of half of cases, either as prima...

BACKGROUND Genital tuberculosis is a common entity in gynecological practice particularly among infertile patients. It is rare in developed countries but is an important cause of infertility in developing countries. OBJECTIVE The present study has investigated the prevalence of female genital tract tuberculosis (FGT) among infertile patients, which was conducted at the Obstetrics and Gynecolo...