نتایج جستجو برای: infection animal models

تعداد نتایج: 1493935  

2016
Shauna A. Marvin

Astroviruses are one of the leading causes of pediatric gastroenteritis worldwide and are clinically importantly pathogens in the elderly and immunocompromised populations. Although the use of cell culture systems and small animal models have enhanced our understanding of astrovirus infection and pathogenesis, little is known about the immune response to astrovirus infection. Studies from human...

Journal: :iranian journal of basic medical sciences 0
leila o zanjani tissue repair lab, institute of biochemistry and biophysics, university of tehran, tehran iran masoumeh firouzi tissue repair lab, institute of biochemistry and biophysics, university of tehran, tehran iran 2 research center for neural repair, university of tehran, tehran, ira mohammad-hossein nabian tissue repair lab, institute of biochemistry and biophysics, university of tehran, tehran iran mohsen nategh tissue repair lab, institute of biochemistry and biophysics, university of tehran, tehran iran vafa rahimi-movaghar research center for neural repair, university of tehran, tehran, iran.sina trauma and surgery research center, tehran university of medical sciences, tehran, iran reza s kamrani department of orthopedics and trauma surgery, shariati hospital, tehran university of medical sciences, tehran, iran

objective (s): scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. this study evaluates the translational capacity of four of physical injury models to induce scar formation around the sciat...

2013
Alexandra I. Stavrakis Jared A. Niska Amanda H. Loftin Fabrizio Billi Nicholas M. Bernthal

Periprosthetic joint infections are devastating complications for patients and for our health system. With growing demand for arthroplasty, the incidence of these infections is projected to increase exponentially. This paper is a review of existing animal models to study periprosthetic infection aimed at providing scientists with a succinct presentation of strengths and weaknesses of available ...

Journal: :Journal of microbiology 2005
Paul A Gulig Keri L Bourdage Angela M Starks

Vibrio vulnificus is an opportunistic pathogen of humans that has the capability of causing rare, yet devastating disease. The bacteria are naturally present in estuarine environments and frequently contaminate seafoods. Within days of consuming uncooked, contaminated seafood, predisposed individuals can succumb to sepsis. Additionally, in otherwise healthy people, V. vulnificus causes wound in...

Journal: :The European respiratory journal 2010
P Martínez-Olondris M Rigol A Torres

Staphylococcus aureus is one of the most common causes of nosocomial pneumonia contributing to significant morbidity and mortality. Therapeutic options for patients with methicillin-resistant S. aureus (MRSA) infection are limited. In addition, little is known about the S. aureus virulence factors that may influence the presentation and prognosis of severe lower respiratory tract infections. An...

Journal: :علوم دامی 0
مسلم ملاعبدالکریمی کارشناس ارشد اصلاح نژاد دام دانشگاه آزاد اسلامی واحد ورامین امیر رشیدی استاد، گروه علوم دامی دانشگاه کردستان قباد عسگری جعفرآبادی استادیار گروه علوم دامی دانشگاه آزاد اسلامی واحد ورامین

in this research, 6517 records, collected by khojir sheep breeding station (tehran, iran), during 1991 to 2011 were used to estimate genetic parameters of lamb survival in zandi sheep. genetic parameters were estimated using 16 different models of animal model, sire and threshold models using reml procedures. the aic criterion was used to evaluate the models. the effects in the most suitable an...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004
Andrea Meyerhoff Renata Albrecht Joette M Meyer Peter Dionne Karen Higgins Dianne Murphy

In August 2000, the US Food and Drug Administration (FDA) approved ciprofloxacin hydrochloride (Cipro; Bayer) for management of postexposure inhalational anthrax. This was the first antimicrobial drug approved by the FDA for use in treating an infection due to a biological agent used intentionally. The terrorist attacks of 2001 involving anthrax underscore the imperative that safe and effective...

2016
Edward D. Chan Xiyuan Bai Diane J. Ordway Deepshikha Verma

The use of animal models has been essential in understanding the pathogenesis of and hosts immune response to tuberculosis, as well as testing potential antimicrobial compounds and vaccines. Experimental animals have also been used to study infections due to non-tuberculous mycobacteria (NTM). Because there are many different species of NTM capable of causing disease and they have varying degre...

Journal: :The American journal of gastroenterology 1989
C M Surawicz L V McFarland G Elmer J Chinn

Recurrence of Clostridium difficile-associated diarrhea and pseudomembranous colitis occurs in up to 20% of patients after standard therapy. In these patients, subsequent recurrences are even more frequent. Saccharomyces boulardii, a nonpathogenic yeast, was found to be effective in preventing clindamycin cecitis recurrence in an animal model. We performed an open trial of S. boulardii to evalu...

Journal: :FEMS immunology and medical microbiology 2004
Jane Blood-Siegfried Burton Shelton

The etiology of sudden infant death syndrome (SIDS) is unknown but thought to be multifactorial. Several animal models have been developed that induce death without pre-existing symptoms and with pathology similar to that seen in SIDS infants; however, the relevance of these animal models to the events leading to SIDS remains elusive, in part because animal models are as varied as the potential...

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