This paper extends the scale-invariant edge detector to the one-dimensional slope. It can accurately detect the slope and estimate its parameters. The method has been verified with several mathematical functions, sample sizes, and noise levels. A contrast-invariant operator is proposed to suppress noise. The inter-sample localization and interpolation greatly improve the accuracy. The proposed ...

Planar cell polarity (PCP) in epithelia, orthogonal to the apical-basal axis, is essential for numerous developmental events and physiological functions. Drosophila model systems have been at the forefront of studies revealing insights into mechanisms regulating PCP and have revealed distinct signaling modules. One of these, involving the atypical cadherins Fat and Dachsous and the ectokinase F...

We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by actin and myosin. We propose that protrusive stresses are only generated where the cell adheres, leading to the cell's effective confinement to the pattern. Co...

Objective(s): Epilepsy establishment gives rise to biochemical and morphological changes in the hippocampus. Oxidative stress, morphological changes, and mossy fiber sprouting (MFS) in the hippocampus underpin the epilepsy establishment. Eugenol is the main component of the essential oil extracted from cloves with the potential to modulate neuronal excitability. Therefore, we investigated the e...

The increasing global interest on traditional and complementary medicine (T/CM) and a need of a centralised and validated information on T/CM, added with a noble mission of optimally integrating the practice of T/CM into the mainstream healthcare system, revolutionised this Commonwealth health minister’s initiative project. Combined with strong government support and strength in ICT infrastruct...

the purpose of this study was to determine the relationship between organizational culture and knowledge management establishment in physical education organization. 120 experts of physical education organization were selected through systematic sampling. two questionnaires (85% validity for organizational culture questionnaire, and 89% validity for knowledge management questionnaire) were used...

Research on intestinal bacteria began around the end of the 19th century. During the last 5 decades of the 20th century, research on the intestinal microbiota made rapid progress. At first, in my work, I first developed a method of comprehensive analysis of the intestinal microbiota, and then I established classification and identification methods for intestinal anaerobes. Using these methods I...

Fibroblasts are fairly easily isolated from a variety of tissues, in this case skin. The cells are fast growing and can be rapidly expanded from small samples. They are suitable for behavioral, functional, biochemical, and genomic studies. Skin fibroblast cultures are started from explants in which the epidermis is enzymatically removed to prevent contamination of the fibroblasts with epidermal...