Cockayne syndrome (CS) is a multisystem degenerative disorder divided in 3 overlapping subtypes, with continuous phenotypic spectrum: CS2 being the most severe form, CS1 classical form and CS3 late-onset form. Failure to thrive growth difficulties are among consistent features of CS, leaving affected individuals vulnerable numerous medical complications, including adverse effects undernutrition...

A novel synthesis of Iimidazo[1,2-c]quinazoline-5(6H)-thione framework was developed through a three-step reaction starting from benzil. The resulting (2-nitrophenyl)-4,5-diphenyl-1H-imidazole  from the reaction of benzil and different 2-nitrobenzaldehyde, reduction of nitro group and then cyclization reaction with carbon disulfide (CS2). All steps were carried out under easy and user-friendly ...

The effects of CS1 duration, partial reinforcement, and trace conditioning on second-order conditioned suppression were investigated, employing 64 rats as Ss. In Experiment 1, the clearest second-order conditioning was obtained when CS1 duration was the same during both the firstand the second-order conditioning phases of the experiment. In Experiment 2, somewhat better second-order conditionin...

Objective—A prospective cohort study was designed to clarify the relations between occupational exposure to carbon disulphide (CS2) and its eVects on arteriosclerosis in workers in 11 Japanese rayon manufacturing factories. This report is a cross sectional baseline observation in the first study year. Methods—Study subjects were 432 male rayon workers (mean (range) age 35.5 (19.1–47.8); duratio...

Running title: The biomechanical and structural properties of CS2 fimbriae „•–”ƒ…–– Enterotoxigenic Escherichia coli (ETEC) are a major cause of diarrhea worldwide, and infection of children in underdeveloped countries often leads to high mortality rates. Isolated ETEC express a plethora of colonization factors (fimbriae/pili), of which CFA/I and CFA/II that are assembled via the alternate chap...

Cloud storage provides a highly available, easily accessible and inexpensive remote data repository to clients who cannot afford to maintain their own storage infrastructure. While many applications of cloud storage require security guarantees against the cloud provider (e.g., storage of high-impact business data or medical records), most services cannot guarantee that the provider will not see...