The present work consists of a numerical and experimental investigation of the effects of the presence of a solid boundary and inertial forces on mass transfer in porous media. Particular emphasis is placed on mass transfer through the porous medium near an impermeable boundary. The local volumeaveraging technique has been used to establish the governing equations. The numerical solution of the...

We study the inviscid limit problem of the incompressible flows in the presence of both impermeable regular boundaries and a hypersurface transversal to the boundary across which the inviscid flow has a discontinuity jump. In the former case, boundary layers have been introduced by Prandtl as correctors near the boundary between the inviscid and viscous flows. In the latter case, the viscosity ...

Cultured mouse peritoneal macrophages were found to be relatively impermeable to streptomycin. Based on radioactivity measurements and radioautographic evidence, macrophages were impermeable to tritiated dihydrostreptomycin for periods up to 20 hr of incubation. Little or no intracellular streptomycin could be detected even when incubation was carried out in the presence of therapeutic blood le...

Drug release mechamsms of swellable systems for controlled drug administration were investigated The variations of the matrix relaxation and drug diffusion rates were quantified, by measuring the surface area exposed during matrix swelling and drug release as a function of impermeable coating coverage and location. Four different types of matrices, partially coated on various sides, were invest...

The present work analyzes the effects of a solid boundary and the inertial forces on flow and heat transfer in porous media. Specific attention is given to flow through a porous medium in the vicinity of an impermeable boundary. The local volume-averaging technique has been utilized to establish the governing equations, along with an indication of physical limitations and assumptions made in th...

Flexible barrier films preventing permeation of gases and moistures are important for many industries ranging from food to medical and from chemical to electronic. From this perspective, graphene has recently attracted particular interest because its defect-free monolayers are impermeable to all atoms and molecules. However, it has been proved to be challenging to develop large-area defectless ...

Oxygen permeability and water diffusion characteristics were determined for several types of hydroxyethyl-methacrylate hydrophilic contact lenses and a silicone contact lens material. A twoto fourfold difference in the diffusion rates for capillary flow of water was found among the different hydrophilic lenses. Oxygen permeability studies demonstrate that the hydrophilic lenses are capable of t...

If the ureter becomes blocked, the resultant increased pressure may be relieved by inserting a double-J stent (a polymer tube, usually punctuated with holes). A major clinical problem associated with stent use is reflux (retrograde flow of urine from the bladder to the kidney), which may result in infections, scarring, and even renal failure. We develop a mathematical model, treating the ureter...

In metazoans, fertilization triggers the assembly of an extracellular coat that constitutes the interface between the embryo and its environment. In nematodes, this coat is the eggshell, which provides mechanical rigidity, prevents polyspermy, and is impermeable to small molecules. Using immunoelectron microscopy, we found that the Caenorhabditis elegans eggshell was composed of an outer vitell...

Bacterial mechanosensitive channels are some of the largest pores in nature. In particular, MscL, with a pore diameter >25 Å, allows passage of large organic ions and small proteins. Functional MscL reconstitution into lipids has been proposed for applications in vesicular-based drug release. Here we show that these channels can be functionally expressed in mammalian cells to afford rapid contr...