نتایج جستجو برای: immunosuppressive drug
تعداد نتایج: 607565 فیلتر نتایج به سال:
Three patients with polymyositis refractory to conventional steroid and immunosuppressive treatment, but responsive to cyclosporin A, are described. In a fourth patient cyclosporin A was used as a first line drug in combination with steroids in the treatment of life-threatening dermatomyositis. Cyclosporin A in the management of polymyositis/dermatomyositis requires formal assessment of its cos...
OBJECTIVE To examine risk of malignancy and death in patients with kidney transplant who receive the immunosuppressive drug sirolimus. DESIGN Systematic review and meta-analysis of individual patient data. DATA SOURCES Medline, Embase, and the Cochrane Central Register of Controlled Trials from inception to March 2013. ELIGIBILITY Randomized controlled trials comparing immunosuppressive r...
Cyclophosphamide, a chemotherapeutic and immunosuppressive drug, has been linked to problems after bone marrow transplantation in the past. More recently, it demonstrated that cardiotoxicity limits dose of cyclophosphamide, cardiology is receiving more attention. Though exact mechanism cyclophosphamide-induced unknown, oxidative nitrative stress are suspected play role. As result, focus this re...
POS0793-HPR OBSERVATIONAL STUDY IN REAL CLINICAL PRACTICE OF THE TREATMENT OF NON-INFECTIOUS UVEITIS
Background Uveitis is an ocular disease that a major cause of morbidity and blindness in the developed world. Although Immunosuppressive drugs biologic therapy have been shown to be effective their treatment there are no clear protocols for use. Objectives To describe characteristics patients with uveitis associated immunologic or idiopathic who require immunosuppressive response real clinical ...
Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe Sandimmune (cyclosporine). Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and supportive medical resources. The physician responsible for maintenance therapy should have complete information requisite for the follow-up o...
mycophenolic acid is a secondary extracellular metabolite of penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. the aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by penicillium brevi-compactum atcc16024 was investigated. batch submerged fer...
Background Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrative database, focusing on demographic and clinical characteristics, and in th...
Tacrolimus (FK506), an immunosuppressive drug, is co-medicated with multiple drugs under clinical conditions. Tacrolimus is highly lipophilic and is excreted from the body after receiving extensive metabolism. Due to its narrow therapeutic window following organ transplantation, tacrolimus requires therapeutic drug monitoring by an enzyme immunoassay using the monoclonal antibody raised against...
Tricho-Dento-Osseous syndrome is a rare autosomal dominant disorder. Immunosuppressive drugs, though critical to the treatment, have undesirable effects on patient's healing process. This is a case report of a 10-year-old female, suffering from Tricho-Dento-Osseous syndrome who was under treatment with penicillamine. As the dental treatment was sought too late, both central and lateral incisors...
Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe Sandimmune (cyclosporine). Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and supportive medical resources. The physician responsible for maintenance therapy should have complete information requisite for the follow-up o...
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