Immunoglobulin G4-related disease (IgG4 RD) is a systemic immune-mediated inflammatory that presents as multiple organ dysfunction or mass lesions with lympho-plasmacytic infiltration. However, there are few case reports presenting central nervous system involvements. Herein, we report of 70-year-old man recurrent ischemic stroke which induced by IgG4 RD. RD should be considered and treated one...

INTRODUCTION Paratesticular fibrous pseudotumors represent benign new growths confined to intrascrotal structures. Both pathogenesis and clinical management are little understood due to the rarity of the lesion, with less than 200 cases reported to date. Recently, paratesticular fibrous pseudotumors have been postulated to be immunoglobulin G4-related, pathogenetically. Here we report two cases...

We present a case of immunoglobulin G4 (IgG4)-related disease with pancreatic and extrapancreatic involvement, including the biliary and renal systems. Given the importance of imaging methods for the diagnosis of IgG4-related disease and its differentiation from pancreatic adenocarcinoma, we emphasize important abdominal computed tomography and magnetic resonance imaging findings related to thi...

Immunoglobulin G4-related disease (IgG4-RD) is a systemic disease characterized by lymphoplasmacytic inflammation, fibrosis, and elevated levels of IgG4 in tissues and eventually in the blood. IgG4-RD is a recently described disease and encompasses classic entities such as Riedel’s thyroiditis, Mikulicz syndrome, and Küttner’s tumor. It is a rare disease that affects middle-aged men, especially...

Immunoglobulin G4 (IgG4)-related disease is a recently defined disease entity, characterized by high serum IgG4 concentration and comprised of a spectrum of systemic disorders, including Mikulicz’s disease; autoimmune pancreatitis; Riedel’s thyroiditis; sclerosing cholangitis; retroperitoneal fibrosis; tubulointerstitial nephritis; and lung lesions, such as hilar lymphadenopathy, pseudotumor an...