I t is not too common to witness the definition of a key, novel biological phenomenon that profoundly influences both our thinking and our approach to an experimental clinical problem. This has been indeed the case, in the field of islet transplantation, with the description of the immediate bloodmediated inflammatory reaction (IBMIR) by Bennet and Korsgren (1–3), because its impact on transpla...

Recently we found that ultraviolet B (UVB) irradiation in erythematous doses significantly inhibited the immediate type hypersensibility reaction in the skin. In the present study we investigated the effects of different wavelengths on the skin prick test reaction (SPT). The forearm of ragweed allergic patients was irradiated with increasing doses of ultraviolet A (UVA), visible light (VIS) or ...

Vasovagal reaction (VVR) is a very common adverse event related to blood donation. No study has been conducted in Pakistan to estimate the prevalence of VVR in blood donors. This study was conducted to estimate the prevalence of immediate VVR in blood donors of Karachi, Pakistan. The study was conducted in two blood banks of Karachi. Data regarding the development of immediate VVR were document...

Mentally challenged individuals are known to have slower speed of reaction. As a previous study has shown immediate improvement in reaction time (RT) following mukha bhastrika, a bellows type of pranayama, we planned to study the effect of this pranayama in mentally challenged adolescents. 34 mentally challenged adolescents (15.1 +/- 0.806 y) studying in a school for Special Needs were recruite...

INTRODUCTION The efficacy of adalimumab, a fully human anti-tumor necrosis factor α recombinant antibody, has dramatically improved the quality of life of patients with rheumatoid and psoriatic arthritis and Crohn's disease. Because it is fully human, one should not expect immune reactions to this molecule. Adverse reactions to adalimumab are limited mainly to injection site reactions and are v...

[Purpose] The aim of this study was to investigate the change in electromechanical reaction times (EMG-RT) of hip flexion of younger persons after neuromuscular joint facilitation (NJF) treatment. [Subjects] The subjects were 39 healthy young people, who were divided into two groups: a NJF group and a proprioceptive neuromuscular facilitation (PNF) group. The NJF group consisted of 16 subjects ...

BACKGROUND & OBJECTIVE The herbal formulation, Gamiseunggal-Tang (G-Tang) has long been used for various allergic diseases. The mechanism of its action is largely unknown. We carried out this study to determine the effect of G-Tang on the mast cell-mediated anaphylactic reactions in vivo and in vitro murine models. METHODS In this study, the effects of G-Tang on the mast cell-mediated anaphyl...