BACKGROUND Sacrococcygeal teratoma (SCT) is a rare congenital tumor and its association with IVF pregnancy is not clear. There are limited reports of congenital tumors in IVF pregnancy. The exact embryogenesis of SCT is not known but a genetic etiology has been reported. Whether these congenital tumors have any association with assisted reproductive techniques remains obscure. CASE PRESENTATI...

Mature cystic teratoma of the ovary is a frequent event, but thyroid papillary carcinoma and strumal carcinoid appear in mature cystic ovarian teratoma at the same time is extremely rare. The present case is the first patient of mature cystic ovarian teratoma with thyroid papillary carcinoma and strumal carcinoid reported from China in English. A review of the literature is performed, and the c...

Malignant ovarian germ cell tumors [MOGCT]are rare cancers occurring in young girls the childbearing age groups. Even advanced stages long term survival rates can be achieved with conservative fertility sparing surgery and chemotherapy. This is a retrospective study of patients diagnosed MOGCT between 2013- 2017. Data 172 eligible were retrieved from electronic medical records. Clinico-patholog...

Two or more histological types characterize more than 60% of testicular germ cell tumors (GCTs). Burned-out testicular tumor refers to partial or complete histological regression of the primary testicular lesions. The most frequent GCT type involved in this kind of histological regression is choriocarcinoma, followed by embryonal carcinoma. To our knowledge, there are no cases of the burned-out...

Neuroendocrine (NE) differentiation is infrequent in testicular tumors and its histogenesis is not well understood. The present study is aimed at elucidating the pathway of neuroendocrine differentiation in germ cell tumors (GCTs) of the testis. In the analysis of 46 germ cell tumor components from 23 testicular tumors, we focused on GCTs with neuroendocrine differentiation, 7 teratoma, 1 embry...

Teratomas are one of the most frequent tumors in the pediatric population. They occur anywhere along the midline of the body, following the course of the embryonic germ cell ridge. In the mediastinal location, they exert space occupying effects, leading to a myriad of complications, including non-immune hydrops fetalis. We describe a fatal case of an immature thymic teratoma in a neonate presen...

Epidermoid cyst of ovary represents 1% of all surface epithelial tumors. Though we commonly see follicular cyst, simple serous cyst, hemorrhagic cysts in hysterectomy specimens of post menopausal females, epidermoid cyst is an incidental finding. It is necessary to differentiate epidermoid cyst from dermoid cyst and immature teratoma because of different line of treatment. We here report a case...

Growing teratoma syndrome (GTS) is a rare clinical entity first described by Logothetis et al in 1982. Although it is unusual for GTS to be located in the ovary, this report is of a case of an adolescent girl who underwent a complete surgical resection of the mass. Histopathology confirmed only an immature teratoma had originated from the ovary and so she received adjuvant chemotherapy with ble...

We aimed to evaluate the histologic components of primary mediastinal mixed germ cell tumors. A total of 221 patients diagnosed with a mediastinal germ cell tumor (GCT) were retrospectively reviewed. Among them, 14 patients underwent surgical resection after chemotherapy and 8 patients were diagnosed with mixed GCT, who were then selected for further evaluation. Clinical chart review and histol...