INTRODUCTION Isolated limb perfusion and infusion (ILP/ILI) are therapies for regional metastatic melanoma that allow high doses of anticancer drugs to be delivered directly into the circulation of an affected limb, thereby minimizing systemic drug toxicity. This procedure can lead to high response rates and is recommended in patients with Stage III unresectable metastatic melanoma. However, li...

BACKGROUND Influenza vaccination is recommended by the World Health Organization for high risk groups, yet few data exist on influenza disease burden in West Africa. METHODS We estimated medically attended influenza-associated illness rates among residents of Shai-Osudoku and Ningo Pram-Pram Districts (SONPD), Ghana. From May 2013 to April 2015, we conducted prospective surveillance for sever...

OBJECTIVE Detailed data are lacking on influenza burden in the United Kingdom (UK). The objective of this study was to estimate the disease burden associated with influenza-like illness (ILI) in the United Kingdom stratified by age, risk and influenza vaccination status. METHODS This retrospective, cross-sectional, exploratory, observational study used linked data from the General Practice Re...

U posljednje dvije godine objavljen je niz vaænih kliniËkih istraæivanja koje produbljuju naπe razumijevanje i kliniËko lijeËenje pacijenata s fibrilacijom atrija (FA). Dva glavna cilja lijeËenja, smanjenje progresije ili ponavljanja aritmije te smanjenje rizika kardiovaskularnih dogaaja, imaju za cilj poboljπanje kvalitete æivota i smanjuje smrtnosti. PrateÊi mnoπtvo dokaza iz predkliniËkih s...

Analysis of Google Influenza-like-illness (ILI) search queries has shown a strongly correlated pattern with Center for Disease Control and Prevention seasonal ILI reporting data. Web and social media (WSM) provide another resource to detect increases in ILI. This paper evaluates trends in blog posts that discuss Influenza. The results of the analysis show Influenza-related blogging trends have ...

krvne æilice mogu izravno promatrati, oftalmoskopija lako i brzo otkriva æilne posljedice hipertenzije (6) (tablica 1). Ipak, pregled oËne pozadine u naπoj se sredini provodi izuzetno, a vrπe ga u pravilu samo oftalmolozi, iako bi ta vrijedna tehnika trebala biti dio svakodnevnoga dijagnostiËkog repertoara, kako internista ili neurologa, tako i obiteljskog lijeËnika. KliniËke posljedice naveden...

The application of the multilingual knowledge encoded in Wikipedia to an open–domain Cross–Lingual Question Answering system based on the Inter Lingual Index (ILI) module of EuroWordNet is proposed and evaluated. This strategy overcomes the problems due to ILI’s low coverage on proper nouns (Named Entities). Moreover, as these are open class words (highly changing), using a community–based up– ...

We analysed an 11-year dataset (1998-2009) of Influenza-Like Illness (ILI) that was based on surveillance of ∽23% of Israel's population. We examined whether the level of synchrony of ILI epidemics in Israel's 12 largest cities is high enough to view Israel as a single epidemiological unit. Two methods were developed to assess the synchrony: (1) City-specific attack rates were fitted to a simpl...

Estimation of influenza infection rates is important for determination of the extent of epidemic spread and for calculation of severity indicators. The authors compared estimated infection rates from paired and cross-sectional serologic surveys, rates of influenza like illness (ILI) obtained from sentinel general practitioners (GPs), and ILI samples that tested positive for influenza using data...

Methods Data from August 2009 to December 2010 were collected. In high-risk patients and those with moderate to severe influenza-like illness (ILI), diagnosis of influenza A and pandemic (H1N1) influenza were confirmed by real-time reverse-transcription polymerase chain reaction (rRT-PCR) by Roche LightCycler 2.0 system. Seven RIDTs were used and results were compared with rRT-PCR to assess per...