Mobile Visitor Information Systems Mobile visitor information systems for fairs, exhibitions, conferences, shopping malls, and similar events, provide the user with a powerful means for organizing his visit and for orientating himself within the event’s surroundings. The Fraunhofer IGD Rostock has developed a rather successful line in such systems, probably the most well known ones being »Mobis...

Haemophilus influenzae (Hi) causes respiratory tract infections and is also considered to be a commensal, particularly in preschool children. Tonsils from patients (n = 617) undergoing tonsillectomy due to chronic infection or hypertrophy were examined. We found that 51% of tonsils were positive for Hi, and in 95% of cases analyzed in detail (n = 39) Hi resided intracellularly in the core tonsi...

Based on their analysis of Internet gaming disorder (IGD) criteria, Kuss, Griffiths, and Pontes (2017) come to the conclusion that the current situation can be described as "chaos and confusion." Their assessment is not an exaggeration. It can be argued that there are even more issues, on logical/definitional and political/social levels: (a) the IGD diagnosis is lacking a well-defined object, (...

Patients with relapsed and refractory multiple myeloma have poor prognosis. A recent analysis of patients with relapsed and refractory multiple myeloma who were refractory to both proteasome inhibitors and immunomodulatory drugs showed the median overall survival of 9 months only. Daratumumab is the first-in-class human monoclonal antibody against CD38 cells which was studied in phase I/II tria...

This commentary paper critically discusses the recent debate paper by Petry et al. (2014) that argued there was now an international consensus for assessing Internet Gaming Disorder (IGD). Our collective opinions vary considerably regarding many different aspects of online gaming. However, we contend that the paper by Petry and colleagues does not provide a true and representative international...

We measured immunoglobulins in the sera of 33 patients on days 1, 3, 6, 10, and 17 and three to four weeks after surgical operations (mostly hysterectomy or appendectomy) or (six patients) after spinal injury. In the absence of infection or blood transfusion, IgG usually decreased slightly and transiently after hysterectomy or appendectomy, as did IgA or IgM after hysterectomy. IgD concentratio...

This document specifies the behavior of the Universal Plug and Play (UPnP) Internet Gateway Device-Port Control Protocol Interworking Function (IGD-PCP IWF). A UPnP IGD-PCP IWF is required to be embedded in Customer Premises (CP) routers to allow for transparent NAT control in environments where a UPnP IGD is used on the LAN side and PCP is used on the external side of the CP router. Informatio...

B lymphocytes undergo affinity maturation of their antigen receptors within germinal centers. These anatomical structures develop in secondary lymphoid organs from the clonal expansion of a few antigen-specific founder B cells, whose isolation and characterization are reported here. Human germinal center founder cells express the naive B cell markers surface IgM and IgD as well as the germinal ...

Interstitial granulomatous dermatitis (IGD) is a rare dermatosis, histologically characterized by an interstitial granulomatous infiltrate. It is associated with inflammatory arthritis, various medications, and autoimmune conditions. It is also associated with malignancies such as breast, endometrial, lung, and esophageal cancers as well as hematologic malignancies such as lymphoma and myelodys...

The ant igen-induced development o f memory B cell populat ions involves both an increase in the number of B cells capable of responding to an antigen and, especially with time and repeated antigen stimulation, a selective expansion of B cells commit ted to producing antibodies with higher combining affinities for the antigen (1). These two events, memory generation and affinity maturat ion, ha...