نتایج جستجو برای: ift
تعداد نتایج: 953 فیلتر نتایج به سال:
Information field theory for cosmological perturbation reconstruction and non-linear signal analysis
IFT and its application. The concepts of IFT are introduced in Sec. II, where Bayesian methodology, the distinction of physical and information fields, the definition of signal response and noise, as well the design of signal spaces are discussed. The basic IFT formalism including the free theory is introduced in Sec. III, which, according to our judgement, summarizes and unifies the previous k...
Wettability alteration has been a sophisticated issue for scientists and reservoir engineers since early 20th century; thus, many investigations have been carried out to determine wettability and enhance it to ideal conditions, which leads to improvement in oil recovery. Dilute surfactant flooding has been approved as one of the noteworthy methods in chemical flooding. Several petroleum reservo...
The application of nanoparticles for enhanced oil recovery (EOR) has been shown to be advantageous over conventional methods. Wettability alteration reservoir rock from oil-wet water-wet is one the main factors in improving matured reservoirs. sandstone reservoirs are generally negatively charged, and hence, a proper selection surface charge important. In this work, novel nanofluid prepared usi...
Sensory neuron cilia are evolutionarily conserved dendritic appendages that convert environmental stimuli into neuronal activity. Although several cilia components are known, the functions of many remain uncharacterized. Furthermore, the basis of morphological and functional differences between cilia remains largely unexplored. To understand the molecular basis of cilia morphogenesis and functi...
The cilium is an important organelle that is found on many eukaryotic cells, where it serves essential functions in motility, sensory reception and signalling. Intraflagellar transport (IFT) is a vital process for the formation and maintenance of cilia. We have determined the crystal structure of Chlamydomonas reinhardtii IFT25/27, an IFT sub-complex, at 2.6 Å resolution. IFT25 and IFT27 intera...
The microtubule (MT) plus-end tracking protein EB1 is present at the tips of cilia and flagella; end-binding protein 1 (EB1) remains at the tip during flagellar shortening and in the absence of intraflagellar transport (IFT), the predominant protein transport system in flagella. To investigate how EB1 accumulates at the flagellar tip, we used in vivo imaging of fluorescent protein-tagged EB1 (E...
Cilia assembly and disassembly are coupled to actin dynamics, ensuring a coherent cellular response during environmental change. How these processes are integrated remains undefined. The histone lysine demethylase KDM3A plays important roles in organismal homeostasis. Loss-of-function mouse models of Kdm3a phenocopy features associated with human ciliopathies, whereas human somatic mutations co...
Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of developmental processes, such as left-right axis specification and limb and neural tube patterning. Genetic studies indicate that IFT proteins are required for Sonic hedgehog (Shh) signaling downstream of the Smoothened and Patched membrane proteins but upstream of the Gli...
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