Die-back of rooibos (Aspalathus linearis) causes substantial losses in commercial Aspalathus plantations in South Africa. In the past, the disease has been attributed to Phomopsis phaseoli (teleomorph: Diaporthe phaseolorum). Isolates obtained from diseased plants, however, were highly variable with regard to morphology and pathogenicity. The aim of the present study was thus to identify the Ph...

Background: Harlequin ichthyosis (HI) is a severe and rare autosomal recessive congenital ichthyosis, characterized by hyperkeratosis, extensive fissuring massive, diamond-shaped scales which limit the child’s movements. The term harlequin comes from baby’s facial expression pattern of like 17th century entertainers, harlequins. underlying genetic abnormality has been identified as mutation in ...

Netherton Syndrome (NS) is a rare hereditary autosomal recessive multisystem disorder which presents with generalized erythroderma at birth or soon after[1]. Its incidence is estimated to be 1/200,000[2]. NS presents in most (but not all) patients with generalized erythroderma and scaling resembling congenital ichthyosiform erythroderma, or continuous peeling of the skin[3]. Other common featur...

Abbreviations: HCG: Human Chorionic Gonadotropin; Β-hCG: Β-Human Chorionic Gonadotropin; DVT: Deep Vein Thrombosis; TMP-SMX: Trimethoprim and Sulfamethoxazole; EBV: Epstein Barr Virus; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; ALP: Alkaline Phosphatase, PT: Prothrombin Time; CBC: Complete Blood Cell; AFLP: Acute Fatty Liver of Pregnancy; DKA: Diabetic Ketoacidosis; GTD: Ge...

The ABCA12 gene encodes an ATP-binding cassette transporter vital to skin barrier function. In keratinocytes, transports ceramides into the lumen of lamellar bodies as part widely conserved water system. Alterations in are associated with autosomal recessive congenital ichthyoses: harlequin ichthyosis, non-bullous ichthyosiform erythroderma, and ichthyosis. We report a 4-month-old female who pr...

Ichthyoses are a heterogeneous group of cutaneous keratinization disorders that can be congenital or acquired. Apart from neoplastic disorders, the acquired form of ichthyosis (AI) has been associated with a variety of diseases including infections, autoimmune/inflammatory and endocrine/metabolic diseases as well as nutritional conditions, medications and others. However, malignancy accounts fo...

Arthrogryposis-renal tubular dysfunction-cholestasis syndrome is a rare multisystem disorder, originally described in 1973 and to date only 62 patients have been reported. Herein, we reported on a neonate with arthrogryposis-renal tubular dysfunction-cholestasis syndrome presenting very early after birth. Recurrent febrile illnesses, failure to thrive, ichthyosis, hypothyroidism, and bilateral ...

Research on the potential biological activity of red alga Symphyocladia spp. has been limited to latiuscula, which is widely used as a food ingredient in Korea. Here, we examined another species, linearis, found Korea and was reported new species 2013. The aim this study evaluate antioxidant, anti-inflammatory, antibacterial properties 70% ethanol extract S. linearis. Antioxidant activity, eval...

We describe a unique presentation of cervical verrucous carcinoma (VC) associated with ichthyosis the uterine cavity in an 80-year old woman. Areas transition from giant condyloma (GC) were present VC. This paper also includes review relevant literature. VC cervix is uncommon malignancy, and GC to interesting finding, confuting theory that they represent distinct entities, different risk factor...