Black brown hyperpigmentation of the mucosae, sunexposed skin, palmar creases and frictional sites (Addisonian pigmentation) is characteristic of Addison disease. However, it can also occur as a paraneoplastic manifestation of tumours like bronchogenic carcinoma. Acquired ichthyosis starts later in life and can also be a paraneoplastic presentation. We report a unique combination of paraneoplas...

otro caso8. Todos los casos descritos tenían afectación palmar. Esta enfermedad puede ser inducida por medicamentos, principalmente por vancomicina2,9,10. Respecto a la fosfomicina como posible desencadenante no se ha descrito la asociación entre este antibiótico y la dermatosis IgA lineal, aunque en el presente caso no podemos descartar que haya actuado como tal. El tratamiento se basa en la a...

Erosive pustular dermatosis is a rare noninfectious disease of the scalp or legs. Clinical findings are nonspecific, with crusts, atrophy, and pustules. A later complication of erosive pustular dermatosis is secondary cicatrical alopecia. The list of possible differential diagnoses is long, and includes infectious, inflammatory, and neoplastic dermatoses. Treatment is challenging. Topical drug ...

n engl j med 372;20 nejm.org may 14, 2015 1972 1. Cohen PR. Sweet’s syndrome — a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis 2007;2:34. 2. Kroshinsky D, Alloo A, Rothschild B, et al. Necrotizing Sweet syndrome: a new variant of neutrophilic dermatosis mim­ icking necrotizing fasciitis. J Am Acad Dermatol 2012;67:945­54. 3. Livneh A, Langevitz P, Zemer D...

Lichen striatus is an acquired, benign, linear inflammatory dermatosis characterized by a sudden skin eruption along Blaschko's lines that usually is not associated with specific etiologic agents. In most cases, it is a self-limited dermatosis, but may relapse. Topical steroids are its first-line therapy, but this treatment is not always effective. We describe the case of a 45-year-old woman af...

Follicular urate-like crystals were first described in Necrotizing Infundibular Crystalline Folliculitis (NICF), a rare cutaneous disorder with multiple waxy folliculocentric papules. Similar crystal accumulation may be seen within follicular infundibulae as an incidental finding. We describe a case showing identical crystals occurring within the horn-like crusts of a patient with erosive pustu...

Among contact dermatosis, irritant contact dermatitis and allergic eczema are by far the most frequent. Nevertheless, concerning occupational dermatosis, contact urticaria should be not neglected. Allergy to natural rubber latex is well-known; however, many other substances found in catering jobs and in jobs involving close contact with animals or vegetables can cause allergies. Discrete forms ...

Sweet syndrome (SS) was first described by Robert Sweet in 1964 as acute febrile neutrophilic dermatosis (Sweet, 1966). Despite of the descriptive value of this denomination and the advice of Robert Sweet to keep it, the eponymous became prevalent on the time. SS was the first neutrofilic dermatosis (ND) described and it represents the paradigm of them. There are three key points of SS that are...

Erythema dyschromicum perstans (EDP) is an acquired dermatosis characterized by ash gray (ashy dermatosis) or blue macules. It can appear at any ageö but is more common in young adults. Lesions may occur on the neck, chest arms and face, but most frequently on the back. It does not generally lead to subjective complaints, but may rarely cause itching. Diagnosis is made with clinical findings an...