نتایج جستجو برای: ibd

تعداد نتایج: 9345  

Journal: :American journal of physiology. Heart and circulatory physiology 2003
Ossama A Hatoum Hiroto Miura David G Binion

THE TWO MAJOR FORMS of human inflammatory bowel disease (IBD), Crohn’s disease (CD) and ulcerative colitis (UC), represent classic chronic inflammatory disorders, characterized by progressive destructive inflammation in the gastrointestinal tract. Although the majority of research into IBD pathogenesis has focused on immune dysregulation, vascular involvement in IBD has also been recognized ove...

2013
Omid Taghavian Holger Spiegel Rüdiger Hauck Hafez M. Hafez Rainer Fischer Stefan Schillberg

Infectious bursal disease virus (IBDV) causes economically important immunosuppressive disease in young chickens. The self-assembling capsid protein (VP2) from IBDV strain IR01 was expressed in Pichia pastoris resulting in the formation of homomeric, 23-nm infectious bursal disease subviral particles (IBD-SVPs) with a yield of 76 mg/l before and 38 mg/l after purification. Anti-IBDV antibodies ...

2015
Fabian Schnitzler Matthias Friedrich Johannes Stallhofer Ulf Schönermarck Michael Fischereder Antje Habicht Nazanin Karbalai Christiane Wolf Marianne Angelberger Torsten Olszak Florian Beigel Cornelia Tillack Burkhard Göke Reinhart Zachoval Gerald Denk Markus Guba Christian Rust Norbert Grüner Stephan Brand Markus M. Heimesaat

BACKGROUND Currently, limited data of the outcome of inflammatory bowel disease (IBD) in patients after solid organ transplantation (SOT) are available. We aimed to analyze effects of SOT on the IBD course in a large IBD patient cohort. METHODS Clinical data from 1537 IBD patients were analyzed for patients who underwent SOT (n = 31) between July 2002 and May 2014. Sub-analyses included SOT o...

2014
AD Spence S McAnearney SJ Murphy SK Bhat M Pitt LJ Murray M Somerville HG Coleman DT McManus BT Johnston JK Eccles TCK Tham G Manikpure C Hutchinson P Ball A Boyle G Ings M Ryan P Allen Loughrey T Owen

Introduction: Inflammatory bowel disease (IBD) requires multiple investigations to assist in disease assessment. Isotope labelled white cell scanning [ILWCS] is sometimes used to assess these patients. ILWCS can be used in the assessment of IBD, although they have no role in the primary diagnosis of IBD. Their utility in terms of influencing management decisions in IBD remains uncertain.

2015
Judith R. Kelsen Robert N. Baldassano David Artis Gregory F. Sonnenberg

Inflammatory bowel disease (IBD) is a multifactoral disease caused by dysregulated immune responses to commensal or pathogenic microbes in the intestine, resulting in chronic intestinal inflammation. An emerging population of patients with IBD occurring before the age of 5 represent a unique form of disease, termed Very Early Onset (VEO)-IBD, which is phenotypically- and genetically-distinct fr...

Journal: :Gastroenterology clinics of North America 2009
Cary G Sauer Subra Kugathasan

Inflammatory bowel disease (IBD) includes Crohn disease and ulcerative colitis, and is often diagnosed in late childhood and early adulthood. What determines the age of onset remains unexplained. Early onset may represent the "pure" form of the disease process and hence may hold secrets of the initiating events of IBD pathogenesis. Clinical scientists continue to focus on pediatric IBD because ...

2018
Maria Pia Costa Santos Catarina Gomes Joana Torres

Familial aggregation in inflammatory bowel disease (IBD) has been established for several decades, reflecting shared genetic and environmental susceptibility. A positive family history remains the strongest recognizable risk factor for the development of IBD and is reported in around 8-12% of IBD patients. Crohn's disease shows a more frequent familial pattern than ulcerative colitis. The risk ...

Journal: :Genetics 2013
Elizabeth A Thompson

Gene identity by descent (IBD) is a fundamental concept that underlies genetically mediated similarities among relatives. Gene IBD is traced through ancestral meioses and is defined relative to founders of a pedigree, or to some time point or mutational origin in the coalescent of a set of extant genes in a population. The random process underlying changes in the patterns of IBD across the geno...

Journal: :International journal of medical microbiology : IJMM 2008
Hiromasa Takaishi Takahiro Matsuki Atsushi Nakazawa Toshihiko Takada Shoichi Kado Takashi Asahara Nobuhiko Kamada Atsushi Sakuraba Tomoharu Yajima Hajime Higuchi Nagamu Inoue Haruhiko Ogata Yasushi Iwao Koji Nomoto Ryuichiro Tanaka Toshifumi Hibi

Since genetically engineered animal models of inflammatory bowel disease (IBD) do not develop colitis under germ-free conditions, the intestinal microflora is thought to be one of the most important environmental factors associated with IBD. To understand the involvement of intestinal microflora in the pathogenesis of IBD, we analyzed the constituents of intestinal microflora in IBD. Faecal sam...

2017
Yen-Chun Peng Cheng-Li Lin Fung-Chang Sung

BACKGROUND & AIMS Inflammatory bowel diseases (IBD) and cholecystectomy are associated with the risk of colorectal cancer (CRC). Our aim was to determine the association between cholecystectomy and the CRC risk in IBD. METHODS We first obtained the Taiwan National Health Insurance Research Database (NHRID), which contains information on approximately 24.7 million insured individuals. A cohort...

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