Objective(s): HTLVI-1 is the first human retrovirus with limited endemic regions in the world. The epidemiological studies have shown that the genetic background and immune response to the virus have a significant role in HTLV-I-associated diseases.  Among the genes are involved in HTLV-I infection, the role of human leukocytes antigen (HLA) have been studied in different population. In the pre...

arsenic trioxide (ato) has been reported to induce apoptosis in leukemic cells of acute promyelo-cytic leukemia (apl) patients through different pathways. however, the exact mechanism of ato-induced apoptosis is not yet clear. co stimulation of death receptors cd30 and tumor necrosis factor receptor type one (tnfr-i) is one of the postulated mechanisms.in the present study we aimed to evaluate ...

investor-state dispute settlement (isds) continues to plague health-oriented government regulation. this is particularly reflected in recent challenges to tobacco control measures through bilateral investment agreements. there are numerous reform proposals circulating within the public health community. however, i suggest that perhaps it is time for the community to explore a stronger position ...

introduction: this study was initiated to examine the effect of the ampullary and the isthmic primary cell cultures of human oviduct during long-term co-culture on two-cell mouse embryos. materials and methods: using a mechanical procedure, epithelial cells from ampullary (a) and isthmic (i) regions of the human oviduct were isolated and cultured in ham's f-10 with 10% fetal calf serum (fsc). t...

With approximate one million new cases every year (Barton, 2012), colon cancer is one of the most severe health burdens all over the world. For stage III colon cancer (T1~4N1~2), standard treatment had been established as radical surgery followed by adjuvant chemotherapy (Moertel et al., 1990; Kuebler et al., 2007; Cassidy et al., 2008) since 1990. However, the treatment outcomes are not as des...