Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) are effective weight loss surgeries that also improve glucose metabolism. Rapid, early rises of circulating insulin and glucagon-like peptide-1 (GLP-1) concentrations following food ingestion are characteristic of these procedures. The purpose of the current study was to test the hypothesis that postprandial hormone release i...

655 VALUE OF CEREBROSPINAL FLUID TUMOR NECROSIS FACTOR-ALPHA (TNF-ALPHA) FOR RAPID DIAGNOSIS OF BACTERIAL MENINGITIS By IMAN FAWZY MONTASSER1, EMAN MOHAMED EL-GINDY1, ENAS HASSAN ALLAM1, HOSAM S. ELBAZ2, REHAM ALI AHMED KHALIFA3 AND HANY EL SAYED ALI Departments of Tropical Medicine1, Internal Medicine2, Microbiology and Immunology3, Faculty of Medicine, Ain Shams University, Cairo 11566 and Em...

Systemic inflammation induces a multiple organ dysfunction syndrome that contributes to morbidity and mortality in septic patients. Since increasing plasma apolipoprotein A-I (apoA-I) and HDL may reduce the complications of sepsis, we tested the hypothesis that the apoA-I mimetic peptide 4F confers similar protective effects in rats undergoing cecal ligation and puncture (CLP) injury. Male Spra...

WhitePaper Foreword This guide is written to serve as inspiration and as an introduction for those who want to know more about eye tracking and how this tool can be used in package and shelf testing. This guide will not explain a methodology but I hope it will inspire you to develop your own methodologies as well as your own tests and experiments. I would also like to thank the people who have ...

Opioids introduced at reperfusion (R) following ischemia (I) reduce infarct size much like postconditioning, suggesting the hypothesis that postconditioning increases cardiac opioids and activates local opioid receptors. Anesthetized male rats subjected to 30 min regional I and 3 h R were postconditioned with three cycles of 10 s R and 10 s reocclusion at onset of R. Naloxone (NL), its peripher...

BACKGROUND Chronic heart failure (CHF) results in limb and respiratory muscle weakness, which contributes to exercise intolerance and increased morbidity and mortality, yet the molecular mechanisms remain poorly understood. Therefore, we aimed to compare parameters of antioxidative capacity, energy metabolism, and catabolic/anabolic balance in diaphragm and quadriceps muscle in an animal model ...

Adenoviral gene transfer of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)2a to the hypertrophic heart in vivo has been consistently reported to lead to enhanced myocardial contractility. It is unknown if the faster skeletal muscle isoform, SERCA1, expressed in the whole heart in early failure, leads to similar improvements and whether metabolic requirements are maintained during an adrenergi...