A 38 yrs old female admitted generalised swelling, puffiness of face and coarsening of features for six months. Examination revealed obesity (BMI 34.7 kg/m) with pitting pedal oedema (Figs, 1,2), normal JVP and delayed relaxation of ankle jerks. Rest of general physical examination and systemic examination was normal. On investigation, haemogram, urine examination, X-ray chest, echocardiography...

Clinical consequences of subclinical hypothyroidism (SH) are still controversial, especially in aging persons. Recently the pleiotropic action of vit. D, also the influence on immune system, was shown and discussed. On the basis of randomly selected 723 women and men (382 men) over 65 yrs old from PolSenior Study we developed the frequency of SH in Polish aging population, and we compared the m...

BACKGROUND Hypothyroidism and dilated cardiomyopathy (DCM) are both common diseases in Doberman Pinschers. A possible influence of hypothyroidism on the etiology and progression of DCM is controversial. OBJECTIVES Evaluation of the role of hypothyroidism in etiology and progression of DCM. ANIMALS A total of 175 Doberman Pinschers. METHODS In this longitudinal prospective study, echocardi...

GOAL To investigate the correlation between TSH and HbA1c in the treatment of L-thyroxine in the process of glycemic control in patients with subclinical hypothyroidism. PATIENTS AND METHODS The sample consisted of 100 patients, mean age 51.75±3.23 years, BMI=27.97±4.52 kg/m(2), with SH (TSH>4.2 mU/L and normal serum T3 and T4). Laboratory diagnosis included the determination of free T3, free...

Objectives. To assess cardiovascular risk factors in Nepalese population with subclinical hypothyroidism as compared to age and sex matched controls. Materials and Methods. A case control study was conducted among 200 subjects (100 subclinical hypothyroid and 100 euthyroid) at B.P. Koirala Institute of Health Sciences, Dharan, Nepal. Demographic and anthropometric variables including systolic a...

Morbid obesity is a metabolic disease characterized by an excessive accumulation of adipose tissue (=40%). This disorder is commonly associated with cardiovascular disease, arteriosclerosis, type 2 diabetes, hypothyroidism and some types of cancer. The most common metabolic signals associated with the disease are leptin, ghrelin, with antagonic effects. Our study aimed at highlighting leptin an...

We hypothesized that regulation of visfatin in hypothyroidism might be altered by coexisting chronic autoimmune thyroiditis. This is a prospective case-control study of 118 subjects. The autoimmune study group (AIT) consisted of 39 patients newly diagnosed with hypothyroidism in a course of chronic autoimmune thyroiditis. The nonautoimmune study group (TT) consisted of 40 patients thyroidectomi...

INTRODUCTION Obesity is a serious public health problem, and the increasing prevalence of overweight status in the population is a major concern worldwide. Fifty eight percent of the Hispanic population of Puerto Rico is obese, but no data are available regarding thyroid status and body mass index (BMI) in this Hispanic group. This study was conducted to investigate if a relationship existed be...