BACKGROUND Our aim was to determine if hyponatremia, defined as serum sodium level < 135 mmol/L, is a predictor of worse outcome in a cohort of real-world patients with heartfailure (HF). METHODS We used data of the National registry of HF (RICA) from Spain, an ongoing multicenter, prospective cohort study. The patients were assigned to two groups regarding sodium levels. Primary end-point wa...

INTRODUCTION Widespread use of generic drugs is considered to be indispensable if reductions in total health care costs are to be achieved, but the market share of such drugs remains low. In general, generic drugs have the same active ingredients as brand-name drugs, but this is not always the case. Thus, toxicity profiles may vary when brand-name and generic drugs are compared. We retrospectiv...

PURPOSE Estimation of body fluid volume in hyponatremia is useful for diagnosis and therapeutic decision-making. Physical examination has been generally used to estimate body fluid volume, but it depends on the physician's abilities. Bioimpedance spectroscopy has been suggested to be a reliable method for the estimation of body fluid volume. Therefore, this study investigated whether bioimpedan...

BACKGROUND Hypothyroidism, commonly induced in preparation for radioiodine treatment of differentiated thyroid cancer, is a text-book cause for hyponatremia. Nausea, stress, and increased fluid intake associated with the treatment are expected to exacerbate hyponatremia. METHODS We prospectively studied 212 (80% females) consecutive thyroid cancer patients for the incidence of hypothyroidism-...

BACKGROUND Hyponatremia is a common electrolyte abnormality in patients with heart failure (HF). It is independently associated with increased short-term and long-term morbidity and mortality. The main objective of this study was to assess patterns of hyponatremia and its association with discharge outcomes in patients with HF admitted to a teaching hospital in Ethiopia. PATIENTS AND METHODS ...

BACKGROUND Hyponatremia is a recognized complication of congestive heart failure (CHF) and is associated with reduced survival. Therefore, early identification and appropriate management of hyponatremia is important. The aim of this study was to determine the general approach amongst Canadian healthcare practitioners and trainees to the identification and management of hyponatremia complicating...

Hyponatremia is the electrolytic disorder most commonly observed among general hospitalized populations, being found in 2% of hospitalized patients. A form of hyponatremia is the syndrome of inappropriate antidiuretic hormone secretion (SIADH). This syndrome consists of faulty urine dilution in the presence of plasma hyposmolality. It is an osmoregulatory disorder that has many causes, includin...

Though tacrolimus-induced nephrotoxicity and hyperkalemia are well known, severe symptomatic hyponatremia is not commonly documented with its use. Here, we report a case of severe symptomatic hyponatremia in a renal transplant recipient on tacrolimus despite normal tacrolimus trough level. All other potential causes of hyponatremia were ruled out in this patient. This case highlights an uncommo...

CARTER, R. Exertional heat illness and hyponatremia: an epidemiological prospective. Curr. Sports Med. Rep., Vol. 7, No. 4, pp. S20YS27, 2008. In active populations, heat illness remains a cause of exercise-related injury and death. There is evidence that hyponatremia also occurs, but less often than heat illness. Incidence rates of these conditions are determined by the population at risk and ...