The influence of different plasma triglyceride concentrations on the heterogeneity of low density lipoprotein (LDL) and on the susceptibility of LDL to copper oxidation was investigated. By density gradient ultracentrifugation, LDL subfractions were isolated from the plasma of 10 normolipidemic control subjects and 12 hypertriglyceridemic patients both before and after clofibrate treatment. In ...

background: waist circumference (wc) is an accurate and simple measure of abdominal obesity as compared to waist–hip ratio (whr). the aim of this study was to determine the correlation between body mass index (bmi) with wc and whr and suggest cutoff points for wc among rural malaysian adults. methods: a cross‑sectional study was conducted among 669 respondents from three villages in tanjung kar...

our aim was to evaluate the association of metabolic syndrome (mets) and its components with body fat percentage (bfp) and anthropometric indicesin10 to 18year old adolescents.this was a cross-sectional study conducted on 134 tehranian adolescents, aged 10 to 18 years (66 boys and 68 girls) in 2007. the mets definition proposed by cook et al. was used. logistic regression was used to determine ...

Triglyceride (TG) metabolism is crucial for whole body and local energy homeostasis and accumulating evidence suggests an independent association between plasma TG concentration and increased atherosclerosis risk. We previously generated a mouse insertional mutation lpd (lipid defect) whose phenotype included elevated plasma TG and hepatic steatosis. Using shotgun sequencing (approximately 500 ...

Lipoprotein compositional studies were carried out in 20 patients with atherosclerotic peripheral vascular disease. Twelve of these patients were normolipidemic, the other eight, hypertriglyceridemic. Ten normolipidemic and 10 hypertriglyceridemic age-matched subjects were used as controls. High density lipoprotein cholesterol levels were markedly reduced in the hypertriglyceridemic subjects, b...

In hypertriglyceridemic subjects, bile acid synthesis measured by isotope dilution is consistently higher than synthesis measured by fecal acidic sterol output. To see which of these two measurements was the more accurate, we compared them to synthesis measured by release of 14CO2 from [26-14C]cholesterol. In 14 hypertriglyceridemic subjects, mean +/- SEM synthesis by the CO2 method was 1540 +/...

Apolipoprotein (apo) E polymorphism was among the first-reported genetic polymorphisms that explained part of the normal variation in plasma cholesterol concentrations in humans. The aim of this study was to assess the influence of allelic variation at the apo E gene locus on the plasma lipoprotein profile in hyperlipidemia. The lipoprotein levels of hyperlipidemic subjects of the major apo E p...

OBJECTIVES The optimal therapy for hypertriglyceridemic acute pancreatitis, especially the role of plasma exchange (PE), is not entirely clear. The aim of our large, single-center, observational, cohort study was to analyze the factors affecting outcome in hypertriglyceridemic pancreatitis treated with PE. METHODS We included 111 episodes of hypertriglyceridemic pancreatitis treated with PE, ...

The influence of different plasma triglyceride concentrations on the heterogeneity of low density lipoprotein (LDL) and on the susceptibility of LDL to copper oxidation was investigated. By density gradient ultracentrifugation, LDL subfractions were isolated from the plasma of 10 normolipidemic control subjects and 12 hypertriglyceridemic patients both before and after clofibrate treatment. In ...