Case presentation: 17-year-old female patient, single child of non-consanguineous healthy parents. The pregnancy and delivery were uneventful. She presented a normal psychomotor development until 4 months age, when she started with epileptic seizures evolved central hypotonia, appendicular hypertonia, dystonia. After, autistic features, stereotypies, lack response to pain, self-harm did not dev...

Because I am a neuromyologist that has dealt for many years with muscle hypertonia, I decided to write my memories in order to motivate younger researchers to try to duplicate the same observations and experiences. We defined a whole range of conditions and symptoms, partly or in full. That is the first crucial step on the way to suppressing or relieving suffering. In some cases there was nothi...

Case presentation: Patient was the first child of non-consanguineous parents whose father healthy, but mother had mild intellectual deficiency and spastic paraparethic gait that been attributed to cerebral palsy. At birth he presented congenital talipes equinovarus. He began crawl at 1yo never able walk independently despite orthopedic feet correction. 1yo, leukocoria in left eye noticed. Bilat...

OBJECTIVE To use an established biomechanical approach to quantify reflex and non-reflex responses from spastic-paretic elbow flexors in response to controlled cold and heat stimulation. METHODS Thirteen spastic-hemiplegic stroke subjects were tested in the experiment. The spastic elbow joint was stretched into extension for 50° at two speeds (5°/s and 100°/s) in a customized apparatus. Therm...

Case presentation: 4 year-old male, diagnosed with Cornelia de Lange syndrome (CdLS). Born preterm at 35 weeks of gestation, the baby weighted 1670 kg and remained in ICU for 25 days. At 1 year age he presented a cephalic perimeter 44cm (microcephaly), horizontal nystagmus extreme lateral gaze, slow saccades, hypertonia hyperreflexia on all four limbs dysmorphic features (hypertelorism, wide no...

OBJECTIVE To determine what biomechanic characteristics of knee joint motion and walking show potential to quantitatively differentiate spasticity and dystonia in cerebral palsy (CP). DESIGN Descriptive measurement study. SETTING University hospital. PARTICIPANTS Seventeen pediatric and adult patients with CP. INTERVENTIONS Not applicable. MAIN OUTCOME MEASURES We measured the resista...