نتایج جستجو برای: hyperlipidemia
تعداد نتایج: 9184 فیلتر نتایج به سال:
BACKGROUND Multiple genetic loci associated with lipid levels have been identified predominantly in Europeans, and the issue of to what extent these genetic loci can predict blood lipid levels increases over time and the incidence of future hyperlipidemia remains largely unknown. METHODS AND RESULTS We conducted a meta-analysis of genome-wide association studies of lipid levels in 8344 subjec...
BACKGROUND The newer antipsychotic agents exhibit a superior safety profile compared with conventional antipsychotic agents in terms of extrapyramidal symptoms. Previous studies have suggested an association between olanzapine treatment and hyperlipidemia. We evaluated this association using a large health care database. METHODS The study was derived from the England and Wales-based General P...
BACKGROUND Hyperlipidemia, which is characterized by an elevation of lipids in the bloodstream, is a major risk factor for cardiac disease. OBJECTIVES The present study investigated the role of fibrosis in the progression of hyperlipidemia in the mice heart, and whether mast cell activation was associated with the fibrosis process. METHODS Hyperlipidemia was produced in C57BL / 6 mice by fe...
RATIONALE Hyperlipidemia and type 2 diabetes mellitus (T2DM) severely impair adaptive vascular growth responses in ischemic muscles. This is largely attributed to dysregulated gene expression, although details of the changes are unknown. OBJECTIVE To define the role of promoter methylation in adaptive vascular growth in hyperlipidemia (LDLR(-/-)ApoB(100/100)) and T2DM (IGF-II/LDLR(-/-)ApoB(10...
BACKGROUND Hyperlipidemia is a common problem after kidney transplantation. OBJECTIVE To uncover the real impact of post kidney transplantation hyperlipidemia on graft function and survival, and to determine whether it is just a biochemical phenomenon after using immunosuppressant or a part of disease pathology. METHODS 330 kidney transplants were managed in Sina Hospital Kidney Transplanta...
BACKGROUND Patients with high levels of total cholesterol (TCH), low-density lipoprotein cholesterol (LDL-CH), and triglyceride (TG) are at increased risk of coronary heart disease. Studies have shown that flavonoids and antioxidant compounds have beneficial effects on hyperlipidemia. OBJECTIVES The aim of the present study was to evaluate the effects of extract of Hypericum perforatum (EHP) ...
BACKGROUND Acupuncture and moxibustion has been widely applied to hyperlipidemia treatment in clinical practice in China, serving as an alternative treatment to statins. Warm-needling acupuncture and medicinal cake-separated moxibustion have been separately reported with potential therapeutic effects on hyperlipidemia treatment in several studies but with limitations in study methodology. Combi...
Maslinic acid is a pentacyclic triterpenoid acid. Recent research has shown that it various biological activities such as anti-tumor, hypoglycaemic and hypolipidemic. Among them, the hypolipidemic effect prominent this study aims to further explore its mechanism of action in treatment hyperlipidemia. The chemical structure maslinic was obtained from PubChem. Based on structure, bioavailability ...
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