OBJECTIVE To report the clinical characteristics of solitary idiopathic choroiditis and the features that differentiate it from tumors and other inflammatory lesions. DESIGN Retrospective medical record review. PATIENTS Sixty consecutive patients with solitary idiopathic choroiditis. MAIN OUTCOME MEASURES Clinical features, natural course, and follow-up. RESULTS The mean and median ages...

BACKGROUND Adenoma of the retinal pigment epithelium (RPE) is a rare intraocular tumor that can simulate other pigmented tumors such as choroidal melanoma. We report a case of non-pigmented adenoma of the RPE initially diagnosed as choroidal hemangioma. CASE REPORT A 42-year-old woman presented to Kurume University Hospital in November 1992 with an orange-yellow tumor nasal to the optic disc ...

Vogt-Koyanagi-Harada disease is an uncommon autoimmune disorder. Its pathophysiology is related to T-cell-mediated autoimmune processes directed against one or more antigenic components of melanocytes. The diagnosis of this condition is primarily based on clinical features including: ocular findings (granulomatous uveitis, choroiditis, exsudative retinal detachment, papillitis) neurological (me...

CHOROIDAL NEVUS Choroidal nevus (Figure 1), the most common primary intraocular tumor,1 is a benign tumor that arises from melanocytic cells derived from the neural crest. Choroidal nevi are more common in white people, with 4% of the population having at least one.1 Malignant transformation into melanoma is possible; therefore, choroidal nevi should be monitored even though the rate is 1 in 4,...

PURPOSE To evaluate the long-term outcomes of anti-vascular endothelial growth factor (VEGF) therapy for polypoidal choroidal vasculopathy (PCV) with feeder vessels and to investigate fellow-eye findings. METHODS This retrospective observational study included 14 eyes with treatment-naïve PCV accompanied by feeder vessels that were treated with anti-VEGF monotherapy. The best-corrected visual...

PURPOSE To report phenotypic characteristics including macular cone photoreceptor morphology in KCNV2-related "cone dystrophy with supernormal rod electroretinogram" (CDSR). METHODS Seven patients, aged 9 to 18 years at last visit, with characteristic full-field electroretinographic (ERG) features of CDSR were screened for mutations in the KCNV2 gene. All patients underwent detailed ophthalmo...

background: the municipal solid wastes (msws) are disposed in open dumps, which have no leachate collection and removal system, in the caspian region of iran. leachate readily reaches the nearby water resources such as streams, rivers, lakes, and sea. therefore, understanding the quality and quantity of open dump leachate is vital to the proper treatment of leachate. methods: the leachate sampl...