the acute intravenous toxicities of a selection of three potential long-acting local anaesthetics belonging to the series of2- phenoxyethyldialkylamine were determined in mice. two of the compounds were tertiary amines and the third a quaternary ammonium derivative.the i.v. median lethal dose, (ldso) of one of the tertiary compounds, 21a [n, n- diethyl-2- (2,6- diisopropyl) ethyl amine hydrochl...

The title compound, [Sn(C(6)H(5))(3)(C(11)H(14)NS(2))], features a tetra-hedrally coordinated Sn atom, as the dithio-carbamate ligand coordinates in a monodentate fashion. Due to the proximity of the non-coordinating thione S atom, distortions from ideal tetra-hedral geometry about the metal atom are evident with the widest C-Sn-S angle being 117.26 (5)°. In the crystal, mol-ecules are linked b...

In this study it is presented the application of spectroscopic methods, such as fluorescence and attenuated total reflection Fourier transform infrared analysis for identification detection secondary metabolite specially, hyoscine, organic functional groups from dry biomass Datura innoxia vegetative organs. The experimental results confirmed presence some important classes metabolites useful in...

Recent years have witnessed the discovery of novel selective agonists of the M(1) muscarinic acetylcholine (ACh) receptor (mAChR). One mechanism invoked to account for the selectivity of such agents is that they interact with allosteric sites. We investigated the molecular pharmacology of two such agonists, 1-[3-(4-butyl-1-piperidinyl)propyl]-3,4-dihydro-2(1H)-quinolinone (77-LH-28-1) and 4-n-b...

Dimeric tri(tert-butyl)cyclopentadienyliron(II) bromide [Cp′′′Fe(μ-Br)]2 (1) reacts with phenylmagnesium bromide to give the dinuclear di(cyclohexadienylidene) complex [(Cp′′′Fe)2(μ ,η5:η5H5C6=C6H5)] (2), and with mesitylmagnesium bromide either to the dinuclear complex [Cp′′′Fe(μ ,η5:η1-C6H2Me3)Fe(Br)Cp′′′] (3) or to the mononuclear mesityl complex [Cp′′′FeC6H2Me3] (4), depending on the reacti...

Background: Previous studies reported that neonatal and maternal complications as well as duration of labor could be diminished through labor management. Therefore, we aimed to evaluate the effect of intramuscular (IM) administration of atropine and hyoscine combination on labor progress and maternal and neonatal outcomes in primigravid women admitted to Taleghani Hospital of Arak, Iran. Metho...