Objective: To assess the efficacy and safety of use midazolam as monotherapy, compared to associated hydroxyzine for minimum moderate sedation children in dental offices, using data obtained from clinical trials. Material Methods: A systematic review protocol was developed registered on PROSPERO (CR42020208633). An electronic search carried out Pubmed, Lilacs, Science Direct, Open Gray, Web Sci...

PURPOSE The purpose of this prospective, double-blind, crossover study was to evaluate the effect of 50% nitrous oxide (N2O) compared to oxygen (O2) alone on behavioral and physiologic parameters when a standard regimen of chloral hydrate (CH) (50 mg/kg) and hydroxyzine (2 mg/kg) was administered to young children for dental procedures. METHODS Twenty children (mean age 42 +/- 7.3 months) wer...

Haloperidol (i.e. HPD) and hydroxyzine (i.e. HXY), two effective and important tranquilizers with low redox activity, were found to generate an irreversible anodic peak at about +0.86 V (vs. SCE) or two anodic peaks at about +0.83 and +0.91 V in 0.05 M NaH₂PO₄-Na₂HPO₄ (pH=7.0) buffer solution with a multi-walled carbon nanotubes-modified glassy carbon electrode (i.e. MWNTs/GC), respectively. Th...

Abstract The current work investigated the efficacy of hybrid treatment process electrocoagulation and adsorption in removing hydroxyzine (HDZ) from polluted aqueous solutions. Response surface methodology (RSM) was used to optimize operating parameters based on sub-category central composite design (CCD). significance variables, interactions, quadratic effects through analysis variance (ANOVA)...

BACKGROUND AND OBJECTIVE While risk of acute kidney injury (AKI) is a well documented adverse effect of some drugs, few studies have assessed the relationship between drug-drug interactions (DDIs) and AKI. Our objective was to develop an algorithm capable of detecting potential signals on this relationship by retrospectively mining data from electronic health records. MATERIAL AND METHODS Dat...