نتایج جستجو برای: hydrazides
تعداد نتایج: 849 فیلتر نتایج به سال:
Aryl hydrazine and hydrazide analogues were synthesized based on p-tolyl hydrazine, isolated as a breakdown product of a secondary metabolite from the mushroom, Agaricus bisporus, and tested to be highly active molecule than 5-fluorouracil in in vitro anticancer studies. The synthesized analogues were tested for anticancer activity using NCI protocol. Anolgues 12 and 15 emerged as molecules wit...
Background: Ofloxacin is a fluoroquinolone antibiotic very useful in the treatment of several bacterial infections. The Thiazolidinone ring system represents privileged structure drug discovery. multi-drug-resistant tuberculosis bacteria infects many people worldwide and disease kills 1.8 million annually, so combination ofloxacin-thiazolidinone ...
There has been considerable interest in the development of novel compounds with anticonvulsant, antioxidant, antibacterial, and antifungal activities. The present study explores antimicrobial activity some new arylidene hydrazide derivatives correlates effect on potency by varying substituents part arylidine hydrazide. Hydrazones possessing an azomethine–NHN=CH- proton constitute important clas...
Abstract A copper-catalyzed radical cross-coupling of cyclobutanone oxime esters with sulfonyl hydrazides has been developed. The copper-based catalytic system proved crucial for cleavage the C−C bond oximes and selective C–S bond-formation involving persistent sulfonyl-metal intermediates. This protocol is distinguished by low-cost system, which does not require ligand, base, or toxic cyanide ...
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