نتایج جستجو برای: hydantoin

تعداد نتایج: 573  

Journal: :Journal of bacteriology 1958
J SZULMAJSTER

Although creatinine is, other than urea, the most important nitrogenous end product excreted by many animals, very little is known about its metabolic pathway in soil bacteria. Some incomplete studies have been made by early workers (Ackerman, 1913, Linneweh, 1930), mostly with putrefactive bacteria, and they claimed to have identified, besides ammonia, methyl-hydantoin as an end product. Dubos...

Journal: :The Journal of antimicrobial chemotherapy 2015
Jennifer Keiser Gordana Panic Mireille Vargas Chunkai Wang Yuxiang Dong Nagsen Gautam Jonathan L Vennerstrom

OBJECTIVES Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandoned antischistosomal Ro 13-3978, an aryl hydantoin discovered in the early 1980s by Hoffmann La-Roche. METHODS Newly transformed schistosomula and adult Schistosoma mansoni were studied in the prese...

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