نتایج جستجو برای: hydantoin
تعداد نتایج: 573 فیلتر نتایج به سال:
Although creatinine is, other than urea, the most important nitrogenous end product excreted by many animals, very little is known about its metabolic pathway in soil bacteria. Some incomplete studies have been made by early workers (Ackerman, 1913, Linneweh, 1930), mostly with putrefactive bacteria, and they claimed to have identified, besides ammonia, methyl-hydantoin as an end product. Dubos...
OBJECTIVES Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandoned antischistosomal Ro 13-3978, an aryl hydantoin discovered in the early 1980s by Hoffmann La-Roche. METHODS Newly transformed schistosomula and adult Schistosoma mansoni were studied in the prese...
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