The title compound, C26H21O3P, was obtained as by-product due to the hydrolysis of the desired tosyl-ated compound. The dihedral angles between the three aromatic rings attached to the P atom lie in the range 78.1 (1)-87.6 (1)°. The hy-droxy-methyl group is disordered between two conformations in a 0.719 (9):0.281 (9) ratio. The hy-droxy H atom is not involved in inter-molecular inter-actions, ...

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The Toll-like receptors (TLRs) are recently discovered germline-encoded receptors on APCs that are critically important in innate immune recognition of microbial pathogens. However, their role in solid-organ transplantation is unknown. To explore this role, we employed a skin allograft model using mice with targeted deletion of the universal TLR signal adaptor protein, MyD88. We report that min...

Tumor-specific delayed hypersensitivity was transferred to peritoneal exÃodate cells obtained from unimmunized strain 2 guinea pigs after the peritoneal exÃodatecells were incubated with RNA-rich extracts from lymphoid tissues of syngeneic guinea pigs previously immunized to either of two antigenically distinct diethylnitrosamine-induced transplantable hepatomas. Tumor-specific delayed hypersen...

Mol-ecules of the title compound, C7H10N2O4, systematic name 5-hy-droxy-5-propyl-pyrimidine-2,4,6(1H,3H,5H)-trione, form a hydrogen-bonded framework which is based on three independent hydrogen bonds, N-H⋯O(carbon-yl), N-H⋯O(hy-droxy) and O-H⋯O(carbon-yl). This framework has the topology of the 5-connected nov net. Each mol-ecule is linked to five other mol-ecules via six hydrogen bonds, and th...

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In the title compound, C18H13ClN2OS·CH3OH, the dihedral angle between the benzimidazole group and the naphth-yloxy moiety [82.89 (5)°] very near to orthogonality. The H atom in the five-membered ring is disordered with equal occupancies at the two N atoms and the H atom of the methano-lic hy-droxy group is disordered with equal occupancies over two sites at the O atom. The methanol mol-ecule ac...

In the title compound, C(13)H(17)NO(3)·0.5H(2)O, a new caffeic acid amide derivative, the solvent water mol-ecule lies on a twofold axis and the terminal ethyl group appears disordered with occupancy factors of 0.525 (6) and 0.475 (6). The benzene ring makes an angle of 17.3 (2)° with the C=C-C-O linker. The presence of an ethyl-enic spacer in the caffeic acid amide mol-ecule allows the formati...

The common structural feature of the title compounds, [Zn(C4H8NOS2)2(C5H5N)]·C5H5N (I) and [Zn(C5H10NOS2)2(C5H5N)]·C5H5N (II), which differ by having di-thio-carbamate N-bound methyl (I) and ethyl (II) groups, is the coordination of each ZnII atom by two non-symmetrically chelating di-thio-carbamate ligands and by a pyridine ligand; in each case, the non-coordinating pyridine mol-ecule is conne...

The title compound, [Cu(C(9)H(6)N(3)O(2))(OH)(H(2)O)(2)](n), adopts a chain motif along [010] in which the Cu(II) atoms are bridged by hy-droxy groups and 4-(1,2,4-triazol-4-yl)benzoate (tab) ligands. The Cu(II) atom lies on an inversion center and is six-coordinated by two N atoms from two tab ligands, two hy-droxy groups and two water mol-ecules, giving a distorted octa-hedral geometry. The h...