BACKGROUND This study compared rates of pregnancy and in vitro fertilization (IVF) parameters in subjects stimulated with follicle stimulating hormone (FSH) plus either recombinant human luteinizing hormone (r-LH) or human menopausal gonadotropin (hMG) in a long gonadotropin releasing hormone (GnRH) agonist IVF protocol. MATERIALS AND METHODS This cohort study enrolled patients who underwent ...

Luteinizing hormone/human chorionic gonadotropin stimulates progesterone biosynthesis in the corpus luteum by activating cyclic adenosine monophosphate/protein kinase A cascade. Recent studies have shown that cyclic adenosine monophosphate-mediated activation of protein kinase A interacts with the mammalian target of rapamycin signaling pathways. Furthermore, the use of mammalian target of rapa...

background: the value of serial measurement of serum ß subunit of human chorionic gonadotropin (ßhcg) and ultrasonography in the early diagnosis of ectopic pregnancy has well established. objective: the objective of this study was to explore the diagnostic value of raising level of serum ßhcg, single measurement of progesterone (p) and estradiol (e2) in early diagnosis of ectopic pregnancy. mat...

Objective: In order to evaluate the endometrium by ultrasound in patients undergoing controlled ovarian hyperstimulation (COH) with clomiphene citrate (CC) and human menopausal gonadotropin (HMG) with intrauterine insemination (IUI) to determine the relationship between endometrial pattern and thickness on pregnancy rate (PR). Methods: In this prospective study, 108 infertile couples under...

Abstract: Introduction: Menopause is an essential part of human life that affects women's quality of life (QOL). Objective: This study investigated the quality of life and some relevant factors in menopausal women. Materials and Methods: This cross-sectional study was conducted on 45-60 years old menopausal women in 3 areas of Kashan city, Iran in 2018. By cluster sampling method, 236 partic...

The existence of a hypothalamic gonadotropin-inhibiting system has been elusive. A neuropeptide named gonadotropin-inhibitory hormone (GnIH, SIKPSAYLPLRF-NH(2)) which directly inhibits gonadotropin synthesis and release from the pituitary was recently identified in quail hypothalamus. Here we identify GnIH homologs in the human hypothalamus and characterize their distribution and biological act...

Urinary estradiol production rates, plasma estradiol, and peripheral conversion of dehydroepiandrosterone sulfate (DHEAS) to estradiol were explored in patients whose neoplasms made human chorionic gonadotropin and/or human chorionic gonadotropin beta fragments. In five men with choriocarcinoma, estradiol production was elevated, plasma estradiol was high, and DHEAS conversion to estradiol rang...

OBJECTIVE To evaluate the relative importance of thyroid hormones and human chorionic gonadotropin in relation to the risk of gestational thyrotoxicosis in Saudi women living in Jeddah, Kingdom of Saudi Arabia. METHODS A prospective study was conducted on Saudi healthy pregnant women (N=406) at 12-15 weeks of gestation and compared with healthy non-pregnant controls (N=200). Maternal serum le...

Introduction: Considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hCG) and that hCG can inhibit myometrial contractions on vitro, made me study treating effects of hCG on preterm labor. This clinical trial study was carried out to compare the effect of hCG, and magnesium sulfate (mgso4) on pre...