background: seroepidemiologic studies indicate a high prevalence of herpes simplex virus (hsv) infection. this infection leads to ophthalmic, dermatologic, oral, neurologic, vaginal and cervical problems. different studies have been carried out to estimate the hsv seroprevalence in iran. combining the results of these studies would be useful for health policy-making.objective: this study aims t...

ICP4 is an important factor regulating the life cycle of HSV1. This conserved protein has several molecular functions, including activation of expression of viral late gene transcripts and inhibition of immediate early genes. Although ICP4 and its Alphaherpesvirinae homologs (eg.: IE62 of VZV) have been subjects of various molecular studies, a complete view of their molecular function is lackin...