A stability-indicating high-performance thin-layer chromatographic (HPTLC) method for determination of tenofovir disoproxil fumarate in bulk drug and in tablet has been developed and validated. The mobile phase selected was chloroform:methanol (9.0:1.0, v/v) with ultraviolet (UV) detection at 260 nm. The retention factor was found to be 0.49 ± 0.03 with correlation coefficients of 0.9994 in the...

A simple, accurate, precise, and specific high-performance thin-layer chromatography (HPTLC) method for the quantitative determination validation of baicalin in different extracts Oroxylum indicum has been developed first time. The mobile phase acetone‒ethyl acetate‒water‒formic acid (2:10:0.5:0.5, V/V) was used achieving good separation. Densitometric carried out at 318 nm. calibration curves ...

Stevioside, a major sweet component of leaves of Stevia rebaudiana (Bertoni), is about 300 times sweeter than sucrose. Highly refined stevia leaf extracts and stevioside are officially used as low calorie sweeteners in many countries. The present study describes a method for rapid identification and estimation of stevioside in commercial samples using HPTLC and HPLC. Identification of steviosid...

Nowadays, plants have been considered as powerful agents for treatment of disorders regarding to their traditional use. In Iranian Traditional Medicine (ITM), plants have a special role in the treatment of various diseases. Burns with their devastating outcomes have been discussed in ITM as well. In the present study, a polyherbal ointment (PHO), retrieved from ITM, was formulated for burn heal...

A simple, accurate and rapid high performance thin layer chromatography (HPTLC)-densitometric method was developed for separation and determination of cetirizine (CET) as a long acting antihistamine and montelukast (MON) as an antileukotriene in pharmaceutical dosage forms. The compounds were separated on silica gel 60 F254 HPTLC plates using a mixture of ethyl acetate : methanol : ammonia solu...

To develop an alternative method for production of sarsasapogenin by plant tissue culture technique and its quantification in Asparagus racemosus and its in vitro cultures using HPTLC. Murashige and Skoog’s (MS) basal medium supplemented with various growth regulators was used for development of shoot and root calli while, hormone free MS medium was used for development of Agrobacterium tumefac...

a simple, accurate and rapid high performance thin layer chromatography (hptlc)-densitometric method was developed for separation and determination of cetirizine (cet) as a long acting antihistamine and montelukast (mon) as an antileukotriene in pharmaceutical dosage forms. the compounds were separated on silica gel 60 f254 hptlc plates using a mixture of ethyl acetate : methanol : ammonia solu...

eight samples of flowering tops from six species of the genus crataegus l., commonly called hawthorn, from different geographic locations of iran were standardized according to german pharmacopoeia monograph on crataegi folium cum flore (hawthorn leaf with flower) by high-performance thin-layer chromatograph-ic (hptlc) fingerprinting combining with digital scanning profiling of their major poly...