Endometrial cancer is a heterogeneous disease. Type I cancers are hormonally driven, typically present with a low grade at an early stage, and are of endometrioid histology. These cancers are often cured by surgery, and the rate of recurrence is low. Type II cancers are less differentiated, often appear at a later stage, and are of serous, clear cell, or high grade endometrioid histology. The r...

4 Androgens.hormonal regulation of spermatogenesis, with an emphasis on the role of testosterone within the. Hormonal messengers are critical not only for regulation of.Spermatogenesis. Cell types involved in sperm production. How they interact to support spermatogenesis. Hormonal regulation of spermatogenesis.ISBN 951-29-2337-8 Print, ł Īī-Ī PDF. The expression and hormonal regulation of beta-...

Additional observations will be presented in this report on the development of mammary cancer in mice, especially virgin females, associated with the action of an inherited hormonal influence, termed the inherited hormonal influence. Comparisons will also be made for the genie make-up of the in herited susceptibility versus the inherited hor monal influence. While the role of the hormonal stimu...

Objective To examine the impact on contraceptive practice of making emergency hormonal contraception available over the counter. Design Analysis of data on contraceptive practice for women aged 16-49 years in the period 2000-2 from the Omnibus Survey, a multipurpose survey in which around 7600 adults living in private households are interviewed each year. Setting Private households in Great Bri...

Substantial heterogeneity exists in weight loss trajectories amongst patients following bariatric surgery. Hormonal factors are postulated to be amongst the contributors to the variation seen. Several hormones involved in hunger, satiety, and energy balance are affected by bariatric surgery, with the alteration in hormonal milieu varying by procedure. Limited research has been conducted to exam...

Obesity is associated with multiple alterations in the endocrine system, including abnormal circulating blood hormone concentrations, which can be due to changes in the pattern of their secretion and/or metabolism, altered hormone transport and/or action at the level of target tissues. In recent years a great stimulus in both basic and clinical research has, on one hand, produced a great deal o...

All methods of contraception have failure rates. Additional failures may occur when interacting drugs are used, and knowledge of these mechanisms should help minimise such problems. This article will look at interactions with hormonal methods of contraception, only some of which, at the present state of knowledge, have clinical significance. The synthetic hormones ethinyloestradiol (EE) and pro...

Many cancers are hormonal related. Estrogen dominance may be accountable for breast, prostate, cervix, endometrial, uterine, and ovarian cancer, for example. Many researchers attribute the high incidence of these cancers to the ubiquitous presence of environmental estrogen (also called xenobiotics) that is present in our food such as commercially raised poultry and cattle; pesticides; and commo...

To cite: Sharp C, Meller M, Moody A, et al. Thorax 2013;68:697–698. A 51-year-old woman presented to the chest clinic with history of progressive dyspnoea and dry cough for 8 weeks. Her past medical history was remarkable for sleeve gastrectomy 3 months ago, which resulted in loss of three stones. She also reported migraines for which she had an implanted occipital nerve stimulator and had unde...

The rising rate of overweight and obesity is a public health crisis in the United States and increasingly around the globe. Rates of contraceptive use are similar among women of all weights, but because contraceptive development studies historically excluded women over 130% of ideal body weight, patients and providers have a gap in understanding of contraceptive efficacy for obese and overweigh...