Foot imbalance is believed to be a common cause of musculoskeletal injury in the horse; its biomechanical effects are, however, poorly understood. Wedges (angle 3.7 and 5 degrees) were attached to modified shoes to elevate one aspect of both front feet of Thoroughbred-type horses. The point of force application during weightbearing was determined at trot using a forceplate system. A total of 8 ...

ABSTRACT We present preliminary results of a bench-scale simulation of the mechanics of dust emissions from a cattle feedyard surface. The experimental apparatus simulated hoof action by dropping steel weights of standardized geometry onto an uncompacted layer of dried, sieved feedyard manure, varying the kinetic energy of the falling weight by adjusting the height from which it was dropped. Th...

Aminopeptidases in the endoplasmic reticulum (ER) can cleave antigenic peptides and in so doing either create or destroy MHC class I-presented epitopes. However, the specificity of this trimming process overall and of the major ER aminopeptidase ERAP1 in particular is not well understood. This issue is important because peptide trimming influences the magnitude and specificity of CD8 T cell res...

This paper describes a new program simplification technique called program trimming that aims to improve the scalability and precision of safety checking tools. Given a program P, program trimming generates a new program P ′ such that P and P ′ are equi-safe (i.e., P ′ has a bug if and only if P has a bug), but P ′ has fewer execution paths than P. Since many program analyzers are sensitive to ...

To gain insight into how sugar chain processing events modulate endoplasmic reticulum (ER)/proteasomal degradation we looked at human asialoglycoprotein receptor polypeptides H2a and H2b, variants which differ only by an extra pentapeptide (EGHRG) present in H2a. Membrane-bound H2a is a precursor of a soluble secreted form while H2b reaches the plasma membrane. Uncleaved precursor H2a molecules...

Semantic caching is a dynamic caching strategy which deals with not only exact but also inexact similar queries, as the local cache has the capability of analyzing the incoming queries. Therefore, in this manner, each query will be carefully analyzed by the cache manager to identify the part that can be retrieved from cache from the part that needs to be retrieved from the server. This trimming...

We carried out lacerations of 50%, followed by trimming, in ten turkey flexor tendons in vitro and measured the coefficient of friction at the tendon-pulley interface with loads of 200 g and 400 g and in 10 degrees , 30 degrees, 50 degrees and 70 degrees of flexion. Laceration increased the coefficient of friction from 0.12 for the intact tendon to 0.3 at both the test loads. Trimming the lacer...

Case DescriptionA twoyear-old female goat with a dark mass on the left hoof was referred to veterinary clinic of Shahid Bahonar University of Kerman. Clinical FindingsA large black and hemorrhagic tumor-like tissue was observed on the left hoof. The epidermis was intact and hairless. Treatment and OutcomeConsidering the good body condition of the patient, the mass was removed surgically. Cefazo...