We read with interest the recent publications by Ariyoshi et al. (2011) and Raccor et al. (2011). The role of a number of cytochrome P450 (P450) isozymes in the 4-hydroxylation of cyclophosphamide has been debated for several years. There is evidence that both CYP2B6 and CYP2C19 are important in the biotransformation and activation of this prodrug in vitro (Chang et al., 1993, 1997; Huang et al...

In Templeton (2010), the Approximate Bayesian Computation (ABC) algorithm (see, e.g., Pritchard et al., 1999, Beaumont et al., 2002, Marjoram et al., 2003, Ratmann et al., 2009) is criticised on mathematical and logical grounds: “the [Bayesian] inference is mathematically incorrect and formally illogical”. Since those criticisms turn out to be bearing on Bayesian foundations rather than on the ...

We praise the article by Mokhtari-Zaer et al. (2015) published in the Avicenna Journal of Phytomedicine on the effects of saffron on smooth muscle activity (Mokhtari-Zaer et al., 2015). It was a well-designed and interesting study on the therapeutic properties of Crocus sativus which is a precious plant cultivated in our country. We do believe that along with all other medicinal effects, saffro...

introduction mineral composition is sensitive to variations in the composition of the magma and can be used to characterize the physical conditions of crystallization such as temperature, pressure, oxygen fugacity and water content. the studies have demonstrated that geobarometery by amphibole provides a tool for determining the depth of crystallization and knowledge of the depth of crystalliza...

The modified histogram shifting method proposed by Hong et. al.(2010) is best method of reversible watermarking[16]. The shifting of pixels are more in Hong et. al.(2010) method. Even Hong et. al.(2010) method of modified histogram shifting has less embedding capacity and do not provide enough quality for general purpose image. Our forward modified histogram shifting method overcomes all these ...

part of its information-gathering activity. The views, conclusions, and recommendations are not intended to represent the views of the Commission. part of its information-gathering activity. The views, conclusions, and recommendations are not intended to represent the views of the Commission. Disclaimer This is a working paper of the World Commission on Dams-the report published herein was prep...

Three new species of the spider genus Philoponella Mello-Leitão, 1917 are described: Philoponella opelli n. sp. from Brazil and Ecuador, and Philoponella fluviidulcifis n. sp. , and Philoponella duopunctata n. sp. from Brazil. New records for Philoponella vittata (Keyserling, 1881), P. republicana (Simon, 1891), P. fasciata (Mello-Leitão, 1917) and P. divisa Opell, 1979 are provided for Brazil ...

J. J. Flint, B. Hansen, S. Portnoy, C. H. Lee, M. A. King, M. Fey, F. Vincent, P. Vestergaard-Poulsen, and S. J. Blackband Neuroscience, University of Florida, Gainesville, Fl, United States, McKnight Brain Institute, University of Florida, Gainesville, Fl, United States, Center for Functionally Integrative Neuroscience, University of Aarhus, Aarhus, Denmark, Electrical Engineering, University ...

Bovine mastitis is very common in cows of both developed and developing countries. The prevalence of clinical and subclinical mastitis (SCM) varies from region to region. Hence, the present study was carried out to determine the prevalence of mastitis using three diagnostic tests by considering different risk factors like age, lactation, breed, season, quarters, and herd. The results showed tha...

BACKGROUND Lejeunea is a largely epiphytic, subcosmopolitan liverwort genus with a complex taxonomic history. Species circumscriptions and their relationships are subject to controversy; biogeographic history and diversification through time are largely unknown. METHODOLOGY AND RESULTS We employed sequences of two chloroplast regions (trnL-trnF, rbcL) and the nuclear ribosomal ITS region of 3...